'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors.
about
The structural basis of arrestin-mediated regulation of G-protein-coupled receptorsPseudorabies virus tegument protein Us2 recruits the mitogen-activated protein kinase extracellular-regulated kinase (ERK) to membranes through interaction with the ERK common docking domain.Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanismsActivity patterns govern synapse-specific AMPA receptor trafficking between deliverable and synaptic poolsLocalization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases.Localization of ERK/MAP kinase is regulated by the alphaherpesvirus tegument protein Us2Phosphorylation of protease-activated receptor-2 differentially regulates desensitization and internalization.ERKed by LRRK2: a cell biological perspective on hereditary and sporadic Parkinson's disease.GPCRs and cancerBeyond desensitization: physiological relevance of arrestin-dependent signaling.Crosstalk between VEGFR2 and muscarinic receptors regulates the mTOR pathway in serum starved SK-N-SH human neuroblastoma cellsPlasma kallikrein promotes epidermal growth factor receptor transactivation and signaling in vascular smooth muscle through direct activation of protease-activated receptors.Combined proteomics and pathways analysis of collecting duct reveals a protein regulatory network activated in vasopressin escape.G Protein and β-arrestin signaling bias at the ghrelin receptor.A single mutation in arrestin-2 prevents ERK1/2 activation by reducing c-Raf1 binding.Oxidative neuronal injury. The dark side of ERK1/2.Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit geneBeta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.Bioinformatic approaches to metabolic pathways analysis.A family of G protein βγ subunits translocate reversibly from the plasma membrane to endomembranes on receptor activation.Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway.The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growthERK and β-arrestin interaction: a converging point of signaling pathways for multiple types of cell surface receptors.Human airway eosinophils exhibit preferential reduction in STAT signaling capacity and increased CISH expression.The inhibitory effect of Gβγ and Gβ isoform specificity on ENaC activity.Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling.Endosomal deubiquitinating enzymes control ubiquitination and down-regulation of protease-activated receptor 2.Class B β-arrestin2-dependent CCR5 signalosome retention with natural antibodies to CCR5.Minireview: More than just a hammer: ligand "bias" and pharmaceutical discovery.The GRK2 Overexpression Is a Primary Hallmark of Mitochondrial Lesions during Early Alzheimer Disease.Light it up: highly efficient multigene delivery in mammalian cells.β-Adrenoceptor Signaling Networks in Adipocytes for Recruiting Stored Fat and Energy Expenditure.β-Arrestin-kinase scaffolds: turn them on or turn them off?Intracellular signaling mechanisms of the melanocortin receptors: current state of the art.Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.Distinct kinetic and spatial patterns of protein kinase C (PKC)- and epidermal growth factor receptor (EGFR)-dependent activation of extracellular signal-regulated kinases 1 and 2 by human nicotinic acid receptor GPR109A.GPR35 as a Novel Therapeutic Target.Suppression of astrovirus replication by an ERK1/2 inhibitor.Distinct pathways of ERK activation by the muscarinic agonists pilocarpine and carbachol in a human salivary cell line.Arrestin mobilizes signaling proteins to the cytoskeleton and redirects their activity.
P2860
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P2860
'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
'Location, location, location' ...... y G protein-coupled receptors.
@ast
'Location, location, location' ...... y G protein-coupled receptors.
@en
type
label
'Location, location, location' ...... y G protein-coupled receptors.
@ast
'Location, location, location' ...... y G protein-coupled receptors.
@en
prefLabel
'Location, location, location' ...... y G protein-coupled receptors.
@ast
'Location, location, location' ...... y G protein-coupled receptors.
@en
P356
P1476
'Location, location, location' ...... y G protein-coupled receptors.
@en
P2093
L M Luttrell
P304
P356
10.1677/JME.0.0300117
P577
2003-04-01T00:00:00Z