Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction
about
Interleukin-1 in the pathogenesis and treatment of inflammatory diseasesInterleukin-18: a therapeutic target in rheumatoid arthritis?The effects of interleukin-18 on rat articular chondrocytes: a study of mRNA expression and protein synthesis of proinflammatory substancesCombined anti-tumor necrosis factor-α therapy and DMARD therapy in rheumatoid arthritis patients reduces inflammatory gene expression in whole blood compared to DMARD therapy aloneThe role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis.Blocking ERK-1/2 reduces tumor necrosis factor alpha-induced interleukin-18 bioactivity in rheumatoid arthritis synovial fibroblasts by induction of interleukin-18 binding protein AIL-32, a proinflammatory cytokine in rheumatoid arthritis.Cellular targets of interleukin-18 in rheumatoid arthritis.IL-1 family cytokines trigger sterile inflammatory disease.Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading.Cytokine networks--towards new therapies for rheumatoid arthritis.Technology insight: gene transfer and the design of novel treatments for rheumatoid arthritis.Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases.Cells of the synovium in rheumatoid arthritis. Chondrocytes.Signalling, inflammation and arthritis: Crossed signals: the role of interleukin-15 and -18 in autoimmunity.Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis.Blocking interleukin-1β in acute and chronic autoinflammatory diseases.Immunomodulation using agonists and antagonists: potential clinical applications.Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes.New developments in the treatment of osteoarthritis - focus on biologic agents.Anti-TNF effects on destructive fibroblasts depend on mechanical stress.Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta.Early response of mouse joint tissue to noninvasive knee injury suggests treatment targets.Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis.The interleukin-1 family gene polymorphisms in Korean patients with rheumatoid arthritis.Wnt/β-catenin and Hedgehog pathways are involved in the inflammatory effect of Interleukin 18 on rat chondrocytes.Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis.
P2860
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P2860
Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Interleukin-18 promotes joint ...... 1-driven cartilage destruction
@ast
Interleukin-18 promotes joint ...... 1-driven cartilage destruction
@en
type
label
Interleukin-18 promotes joint ...... 1-driven cartilage destruction
@ast
Interleukin-18 promotes joint ...... 1-driven cartilage destruction
@en
prefLabel
Interleukin-18 promotes joint ...... 1-driven cartilage destruction
@ast
Interleukin-18 promotes joint ...... 1-driven cartilage destruction
@en
P2093
P2860
P1476
Interleukin-18 promotes joint ...... 1-driven cartilage destruction
@en
P2093
Birgitte Oppers-Walgreen
Erik Lubberts
Fons A J van de Loo
Leo A B Joosten
Liduine A M van den Bersselaar
Monique M A Helsen
Ruben L Smeets
Wim B van den Berg
Yoichiro Iwakura
P2860
P304
P356
10.1016/S0002-9440(10)63357-3
P407
P577
2004-09-01T00:00:00Z