The Regulation of Aging and Longevity: A New and Complex Role of p53.
about
ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related DiseasesGlobal view of transcriptome in the brains of aged NR2B transgenic miceIntroduction: The Changing Directions of p53 Research.Np9, a cellular protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin ligase MDM2.Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice.Unfolded protein response is activated in aged retinas.Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis.Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging.Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature agingSelective anticancer agents suppress aging in DrosophilaNew nucleophilic mechanisms of ros-dependent epigenetic modifications: comparison of aging and cancer.Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression.Senescence regulation by the p53 protein familyModelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri.Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.Helicobacter pylori Infection Activates the Akt-Mdm2-p53 Signaling Pathway in Gastric Epithelial Cells.Multiple Metazoan Life-span Interventions Exhibit a Sex-specific Strehler-Mildvan Inverse Relationship Between Initial Mortality Rate and Age-dependent Mortality Rate Acceleration.Human Periosteal Derived Stem Cell Potential: The Impact of age.Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner.Relevance of the p53-MDM2 axis to aging.Δ133p53 represses p53-inducible senescence genes and enhances the generation of human induced pluripotent stem cells.TP53*P72 allele influences negatively female life expectancy in a population of central Italy: cross-sectional study and genetic-demographic approach analysis.A switch-like dynamic mechanism for the initiation of replicative senescence.
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P2860
The Regulation of Aging and Longevity: A New and Complex Role of p53.
description
2011 nî lūn-bûn
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2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
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2011年论文
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name
The Regulation of Aging and Longevity: A New and Complex Role of p53.
@ast
The Regulation of Aging and Longevity: A New and Complex Role of p53.
@en
type
label
The Regulation of Aging and Longevity: A New and Complex Role of p53.
@ast
The Regulation of Aging and Longevity: A New and Complex Role of p53.
@en
prefLabel
The Regulation of Aging and Longevity: A New and Complex Role of p53.
@ast
The Regulation of Aging and Longevity: A New and Complex Role of p53.
@en
P2093
P2860
P356
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The Regulation of Aging and Longevity: A New and Complex Role of p53.
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P2093
P2860
P304
P356
10.1177/1947601911410223
P577
2011-04-01T00:00:00Z