AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3. - Wikidata - wikimedia - TriplyDB

AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.

AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.

http://www.wikidata.org/entity/Q35103810

about

Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway.Lowering glucose level elevates [Ca2+]i in hypothalamic arcuate nucleus NPY neurons through P/Q-type Ca2+ channel activation and GSK3β inhibition.Phosphorylation of amyloid precursor protein at threonine 668 is essential for its copper-responsive trafficking in SH-SY5Y neuroblastoma cells.ATF6 mediates a pro-inflammatory synergy between ER stress and TLR activation in the pathogenesis of liver ischemia-reperfusion injury.Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction Synergistic anti-cancer effect of phenformin and oxamate.Intracellular signaling pathways regulating net protein balance following diaphragm muscle denervation.(4-[6-(4-isopropoxyphenyl)pyrazolo [1,5-a]pyrimidin-3-yl] quinoline) is a novel inhibitor of autophagy Metabolic regulation of cancer cell side population by glucose through activation of the Akt pathway."Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells".Mitochondrial oxidative stress corrupts coronary collateral growth by activating adenosine monophosphate activated kinase-α signaling.AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation.Apoptotic cells activate AMP-activated protein kinase (AMPK) and inhibit epithelial cell growth without change in intracellular energy stores A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension.Chloroquine increases phosphorylation of AMPK and Akt in myotubes.AKT pathway in neuroblastoma and its therapeutic implication.Leptin inhibits glycogen synthase kinase-3beta to prevent tau phosphorylation in neuronal cells.AMPK inhibitor Compound C stimulates ceramide production and promotes Bax redistribution and apoptosis in MCF7 breast carcinoma cells.Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation.Impact of 5'-amp-activated Protein Kinase on Male Gonad and Spermatozoa Functions Roles of AMP-activated protein kinase in Alzheimer's disease.Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity.The Paradox of Akt-mTOR Interactions.The multifaceted activities of AMPK in tumor progression--why the "one size fits all" definition does not fit at all?Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d.Adiponectin attenuates Ang Ⅱ-induced TGFβ1 production in human mesangial cells via an AMPK-dependent pathway.Activation of AMP-activated protein kinase alleviates homocysteine-mediated neurotoxicity in SH-SY5Y cells.Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts.Protection from interferon-β-induced neuronal apoptosis through stimulation of muscarinic acetylcholine receptors coupled to ERK1/2 activation.AMPK exerts dual regulatory effects on the PI3K pathway.Activation of peroxisome proliferator-activated receptor beta/delta induces lung cancer growth via peroxisome proliferator-activated receptor coactivator gamma-1alpha.Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression.Interference with energy metabolism by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside induces HPV suppression in cervical carcinoma cells and apoptosis in the absence of LKB1.Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia.AMP-activated protein kinase: a therapeutic target in intestinal diseases.

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P2860

AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3.

http://www.wikidata.org/entity/Q35103810

description

2006 nî lūn-bûn

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2006 թուականի Մարտին հրատարակուած գիտական յօդուած

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2006 թվականի մարտին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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AMP-activated protein kinase ( ...... nd glycogen synthase kinase-3.

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J.BCP.2006.03.005

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Biochemical Pharmacology

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AMP-activated protein kinase ( ...... nd glycogen synthase kinase-3.

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P2093

Ling Song

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Richard S Jope

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Taj D King

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P2860

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

Role of AMP-activated protein kinase in mechanism of metformin action

The AMP-activated protein kinase prevents ceramide synthesis de novo and apoptosis in astrocytes

Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage

Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

The AMP-activated protein kinase cascade--a unifying system for energy control

Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

Cytokine regulation of neuronal differentiation of hippocampal progenitor cells

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

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1637-1647

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11

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7159038

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16620785

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1618797

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