The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
about
Evidence that ebolaviruses and cuevaviruses have been diverging from marburgviruses since the MioceneEffective post-exposure treatment of Ebola infectionHuman fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosisFiloviral immune evasion mechanismsDRBP76 associates with Ebola virus VP35 and suppresses viral polymerase functionHerpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcomeInhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virusEbola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responsesInhibition of RIG-I-dependent signaling to the interferon pathway during hepatitis C virus expression and restoration of signaling by IKKepsilon.Marburgvirus genomics and association with a large hemorrhagic fever outbreak in AngolaRotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3Emerging targets and novel approaches to Ebola virus prophylaxis and treatmentInnate cellular response to virus particle entry requires IRF3 but not virus replicationRotavirus nonstructural protein 1 suppresses virus-induced cellular apoptosis to facilitate viral growth by activating the cell survival pathways during early stages of infectionEbola haemorrhagic feverInhibition of interferon signaling by dengue virusThe Role of Cytokines and Chemokines in Filovirus InfectionFiloviruses: One of These Things is (not) Like the OtherAddressing the Complications of Ebola and Other Viral Hemorrhagic Fever Infections: Using Insights from Bacterial and Fungal SepsisShedding light on filovirus infection with high-content imagingLoss of interferon regulatory factor 3 in cells infected with classical swine fever virus involves the N-terminal protease, NproWest Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling.Classical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal DegradationCapsid Protein of Eastern Equine Encephalitis Virus Inhibits Host Cell Gene ExpressionMurine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/MicrogliaMarburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola VirusModulation of type I IFN induction by a virulence determinant within the alphavirus nsP1 proteinRabies Virus Nucleoprotein Functions To Evade Activation of the RIG-I-Mediated Antiviral ResponseEbolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppressionStructure of the Ebola VP35 interferon inhibitory domainMutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea PigsStructural basis for dsRNA recognition and interferon antagonism by Ebola VP35Structural and Functional Characterization of Reston Ebola Virus VP35 Interferon Inhibitory DomainMarburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon AntagonismStructural basis for Marburg virus VP35-mediated immune evasion mechanismsEbolavirus VP35 Coats the Backbone of Double-Stranded RNA for Interferon AntagonismDevelopment of RNA Aptamers Targeting Ebola Virus VP35In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity
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P2860
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
@ast
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
@en
type
label
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
@ast
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
@en
prefLabel
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
@ast
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
@en
P2093
P2860
P50
P1433
P1476
The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
@en
P2093
Andrea Mikulasova
Jason Paragas
P2860
P304
P356
10.1128/JVI.77.14.7945-7956.2003
P407
P50
P577
2003-07-01T00:00:00Z