Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures - Wikidata - wikimedia - TriplyDB

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

http://www.wikidata.org/entity/Q35105223

about

Structural mechanism of trimeric HIV-1 envelope glycoprotein activation Dynamic Viral Glycoprotein Machines: Approaches for Probing Transient States That Drive Membrane Fusion Structures of viral membrane proteins by high-resolution cryoEM HIV-1 envelope glycoprotein structure Catching HIV 'in the act' with 3D electron microscopy A Chimeric HIV-1 gp120 Fused with Vaccinia Virus 14K (A27) Protein as an HIV Immunogen A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer Structure-Based Reverse Vaccinology Failed in the Case of HIV Because it Disregarded Accepted Immunological Theory Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies Recent advances on the use of structural biology for the design of novel envelope immunogens of HIV-1 HIV-1 variable loop 2 and its importance in HIV-1 infection and vaccine development Controlling the HIV/AIDS epidemic: current status and global challenges Determination of molecular structures of HIV envelope glycoproteins using cryo-electron tomography and automated sub-tomogram averaging.Dynamic electrophoretic fingerprinting of the HIV-1 envelope glycoprotein.Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120 Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain.Antigenic and 3D structural characterization of soluble X4 and hybrid X4-R5 HIV-1 Env trimers Visualization of retroviral envelope spikes in complex with the V3 loop antibody 447-52D on intact viruses by cryo-electron tomography.Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site.Rational design and characterization of the novel, broad and potent bispecific HIV-1 neutralizing antibody iMabm36.Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers.Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer Cryo-electron microscopy--a primer for the non-microscopist.CD4-induced activation in a soluble HIV-1 Env trimer.Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives.HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage.A mechanistic understanding of allosteric immune escape pathways in the HIV-1 envelope glycoprotein.Epitope mapping of M36, a human antibody domain with potent and broad HIV-1 inhibitory activity.Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.Functional characterization of two scFv-Fc antibodies from an HIV controller selected on soluble HIV-1 Env complexes: a neutralizing V3- and a trimer-specific gp41 antibody.A mammalian cell based FACS-panning platform for the selection of HIV-1 envelopes for vaccine development Membrane-proximal external HIV-1 gp41 motif adapted for destabilizing the highly rigid viral envelope

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Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures

http://www.wikidata.org/entity/Q35105223

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Trimeric HIV-1 glycoprotein gp ...... ernary molecular architectures

@ast

Trimeric HIV-1 glycoprotein gp ...... ernary molecular architectures

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type

label

Trimeric HIV-1 glycoprotein gp ...... ernary molecular architectures

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Trimeric HIV-1 glycoprotein gp ...... ernary molecular architectures

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Trimeric HIV-1 glycoprotein gp ...... ernary molecular architectures

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Trimeric HIV-1 glycoprotein gp ...... ernary molecular architectures

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PNAS.1101414108

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Trimeric HIV-1 glycoprotein gp ...... ernary molecular architectures

@en

P2093

Alberto Bartesaghi

http://www.w3.org/2001/XMLSchema#string

Andre J Marozsan

http://www.w3.org/2001/XMLSchema#string

Audray Harris

http://www.w3.org/2001/XMLSchema#string

Dan Shi

http://www.w3.org/2001/XMLSchema#string

Haifeng He

http://www.w3.org/2001/XMLSchema#string

Jacqueline L S Milne

http://www.w3.org/2001/XMLSchema#string

John P Moore

http://www.w3.org/2001/XMLSchema#string

Mario J Borgnia

http://www.w3.org/2001/XMLSchema#string

Per Johan Klasse

http://www.w3.org/2001/XMLSchema#string

Rafael Depetris

http://www.w3.org/2001/XMLSchema#string

P2860

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

Molecular architecture of native HIV-1 gp120 trimers

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

The HIV Env-mediated fusion reaction

GP120: target for neutralizing HIV-1 antibodies

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

P304

11440-11445

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scholarly article

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10.1073/PNAS.1101414108

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P433

28

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108

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Ian Andrew Wilson

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2011-06-27T00:00:00Z

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51253725

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21709254

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3136299

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