Importazole, a small molecule inhibitor of the transport receptor importin-β - Wikidata - wikimedia - TriplyDB

Importazole, a small molecule inhibitor of the transport receptor importin-β

Importazole, a small molecule inhibitor of the transport receptor importin-β

http://www.wikidata.org/entity/Q35109174

about

RanGTP and CLASP1 cooperate to position the mitotic spindle.Structural Basis of Targeting the Exportin CRM1 in Cancer Fine-tuning multiprotein complexes using small molecules The G protein α chaperone Ric-8 as a potential therapeutic target Rapid flow cytometric measurement of protein inclusions and nuclear trafficking.Human mutations affect the epigenetic/bookmarking function of HNF1B Essential elements for translation: the germline factor Vasa functions broadly in somatic cells.Personalization of the immunosuppressive treatment in renal transplant recipients: the great challenge in "omics" medicine NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.Chromosomal gain promotes formation of a steep RanGTP gradient that drives mitosis in aneuploid cells.Subcellular knockout of importin β1 perturbs axonal retrograde signaling.Live cell imaging of protein dislocation from the endoplasmic reticulum.Microtubule-dependent regulation of mitotic protein degradation.Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons.Targeting nucleocytoplasmic transport in cancer therapy Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis.Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighbors Positional Scanning Synthesis of a Peptoid Library Yields New Inducers of Apoptosis that Target Karyopherins and Tubulin.Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites Nuclear transport factors: global regulation of mitosis.Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent KPNB1 mediates PER/CRY nuclear translocation and circadian clock function.Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency.Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.Nuclear import of the thyroid hormone receptor α1 is mediated by importin 7, importin β1, and adaptor importin α1 Androgen receptor splice variants circumvent AR blockade by microtubule-targeting agents Nucleosome functions in spindle assembly and nuclear envelope formation.RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence.Nuclear glutaredoxin 3 is critical for protection against oxidative stress-induced cell death Nuclear translocation of annexin 1 following oxygen-glucose deprivation-reperfusion induces apoptosis by regulating Bid expression via p53 binding.Increases in Retrograde Injury Signaling Complex-Related Transcripts in Central Axons following Injury.Towards Engineering Novel PE-Based Immunotoxins by Targeting Them to the Nucleus HDAC10 promotes lung cancer proliferation via AKT phosphorylation.Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration.TRIP13-deficient tubular epithelial cells are susceptible to apoptosis following acute kidney injury.Stimulated nuclear import by β-like importins.Importin β-dependent nuclear import of TopBP1 in ATR-Chk1 checkpoint in Xenopus egg extracts.

P2860

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P2860

Importazole, a small molecule inhibitor of the transport receptor importin-β

http://www.wikidata.org/entity/Q35109174

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Importazole, a small molecule inhibitor of the transport receptor importin-β

@ast

Importazole, a small molecule inhibitor of the transport receptor importin-β

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type

label

Importazole, a small molecule inhibitor of the transport receptor importin-β

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Importazole, a small molecule inhibitor of the transport receptor importin-β

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prefLabel

Importazole, a small molecule inhibitor of the transport receptor importin-β

@ast

Importazole, a small molecule inhibitor of the transport receptor importin-β

@en

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P1433

ACS Chemical Biology

P1476

Importazole, a small molecule inhibitor of the transport receptor importin-β

@en

P2093

Jonathan F Soderholm

http://www.w3.org/2001/XMLSchema#string

Keisuke Hasegawa

http://www.w3.org/2001/XMLSchema#string

Michael Uehara-Bingen

http://www.w3.org/2001/XMLSchema#string

Petr Kalab

http://www.w3.org/2001/XMLSchema#string

Stephen L Bird

http://www.w3.org/2001/XMLSchema#string

Yasaswini Sampathkumar

http://www.w3.org/2001/XMLSchema#string

P2860

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

A novel receptor-mediated nuclear protein import pathway

Identification of different roles for RanGDP and RanGTP in nuclear protein import

Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-beta2 and RanGTP

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

Importin-beta-like nuclear transport receptors

The karyopherin Kap95 regulates nuclear pore complex assembly into intact nuclear envelopes in vivo.

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

Leptomycin B targets a regulatory cascade of crm1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression

P304

700-708

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scholarly article

P356

10.1021/CB2000296

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7

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6

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51029087

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21469738

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3137676

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