ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons
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The DLK signalling pathway--a double-edged sword in neural development and regenerationIntrinsic Axonal Growth and the Drive for RegenerationZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonatesFunctional decline at the aging neuromuscular junction is associated with altered laminin-α4 expression.DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activityCytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury.Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoformFunctional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death.Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signalingLeucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons.Loss of the spectraplakin short stop activates the DLK injury response pathway in Drosophila.Spatial and temporal dynamics of neurite regrowth.Dual leucine zipper kinase regulates expression of axon guidance genes in mouse neuronal cells.Rho1-Wnd signaling regulates loss-of-cell polarity-induced cell invasion in Drosophila.Dual leucine zipper kinase is required for retrograde injury signaling and axonal regeneration.Tozasertib attenuates neuronal apoptosis via DLK/JIP3/MA2K7/JNK pathway in early brain injury after SAH in ratsCausation of Acute Flaccid Paralysis by Myelitis and Myositis in Enterovirus-D68 Infected Mice Deficient in Interferon αβ/γ Receptor Deficient Mice.DLK silencing attenuated neuron apoptosis through JIP3/MA2K7/JNK pathway in early brain injury after SAH in rats.Zika virus-induced acute myelitis and motor deficits in adult interferon αβ/γ receptor knockout mice.Distinct homeostatic modulations stabilize reduced postsynaptic receptivity in response to presynaptic DLK signaling.Intrathecal Injection of Dual Zipper Kinase shRNA Alleviating the Neuropathic Pain in a Chronic Constrictive Nerve Injury Model
P2860
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P2860
ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons
description
2011 nî lūn-bûn
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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2011 թվականի մայիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
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2011年论文
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name
ZPK/DLK, a mitogen-activated p ...... mmed cell death of motoneurons
@ast
ZPK/DLK, a mitogen-activated p ...... mmed cell death of motoneurons
@en
type
label
ZPK/DLK, a mitogen-activated p ...... mmed cell death of motoneurons
@ast
ZPK/DLK, a mitogen-activated p ...... mmed cell death of motoneurons
@en
prefLabel
ZPK/DLK, a mitogen-activated p ...... mmed cell death of motoneurons
@ast
ZPK/DLK, a mitogen-activated p ...... mmed cell death of motoneurons
@en
P2093
P2860
P1476
ZPK/DLK, a mitogen-activated p ...... mmed cell death of motoneurons
@en
P2093
David Pleasure
Kouji Wakayama
Makoto Horiuchi
Peter Bannerman
Takayuki Itoh
P2860
P304
P356
10.1523/JNEUROSCI.5947-10.2011
P407
P577
2011-05-01T00:00:00Z