Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).
about
Endoplasmic reticulum chaperones and oxidoreductases: critical regulators of tumor cell survival and immunorecognitionCancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 productionA long non-coding RNA signature to improve prognosis prediction of colorectal cancer.Triptolide activates unfolded protein response leading to chronic ER stress in pancreatic cancer cells.Microenvironment, oncoantigens, and antitumor vaccination: lessons learned from BALB-neuT mice.CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signalling in ovarian cancer cells.Data-driven modeling of SRC control on the mitochondrial pathway of apoptosis: implication for anticancer therapy optimization.Bcl-2 family proteins in breast development and cancer: could Mcl-1 targeting overcome therapeutic resistance?Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers.GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach.Interplay between unfolded protein response and autophagy promotes tumor drug resistanceRole of GRP78 in promoting therapeutic-resistant breast cancerRole of the unfolded protein response, GRP78 and GRP94 in organ homeostasis.Models and Mechanisms of Acquired Antihormone Resistance in Breast Cancer: Significant Clinical Progress Despite Limitations.Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsivenessControl of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s.Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer.Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells.Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasisOverexpression of molecular chaperons GRP78 and GRP94 in CD44(hi)/CD24(lo) breast cancer stem cells.The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapiesTriptolide-mediated inhibition of interferon signaling enhances vesicular stomatitis virus-based oncolysis.Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis ProgressionEffects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice.Plumbagin sensitizes breast cancer cells to tamoxifen-induced cell death through GRP78 inhibition and Bik upregulation.The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo.Targeting GRP78 and antiestrogen resistance in breast cancer.Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potentialA stressful microenvironment: opposing effects of the endoplasmic reticulum stress response in the suppression and enhancement of adaptive tumor immunity.Retrospective Proteomic Screening of 100 Breast Cancer Tissues.LncRNA-TP53TG1 Participated in the Stress Response Under Glucose Deprivation in Glioma.Glucose-regulated protein 78 mediates the anticancer efficacy of shikonin in hormone-refractory prostate cancer cells.Cell-type variation in stress responses as a consequence of manipulating GRP78 expression in neuroectodermal cells.Genes and gene networks involved in sodium fluoride-elicited cell death accompanying endoplasmic reticulum stress in oral epithelial cellsKnockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxiaInvolvement of ER-α36 in the malignant growth of gastric carcinoma cells is associated with GRP94 overexpression.Selenium mediated arsenic toxicity modifies cytotoxicity, reactive oxygen species and phosphorylated proteins.Targeting the unfolded protein response in cancer.Expressions of GRP78 and Bax associate with differentiation, metastasis, and apoptosis in non-small cell lung cancer.Helicobacter pylori outer inflammatory protein A (OipA) suppresses apoptosis of AGS gastric cells in vitro.
P2860
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P2860
Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Novel mechanism of anti-apopto ...... CL-2-interacting killer (BIK).
@ast
Novel mechanism of anti-apopto ...... CL-2-interacting killer (BIK).
@en
type
label
Novel mechanism of anti-apopto ...... CL-2-interacting killer (BIK).
@ast
Novel mechanism of anti-apopto ...... CL-2-interacting killer (BIK).
@en
prefLabel
Novel mechanism of anti-apopto ...... CL-2-interacting killer (BIK).
@ast
Novel mechanism of anti-apopto ...... CL-2-interacting killer (BIK).
@en
P2093
P2860
P356
P1476
Novel mechanism of anti-apopto ...... BCL-2-interacting killer (BIK)
@en
P2093
P2860
P304
25687-25696
P356
10.1074/JBC.M110.212944
P407
P577
2011-05-26T00:00:00Z