Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
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A(a)LS: Ammonia-induced amyotrophic lateral sclerosis.The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the ProteasomeAMPK Signalling and Defective Energy Metabolism in Amyotrophic Lateral Sclerosis.Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice.Early ALS-type gait abnormalities in AMP-dependent protein kinase-deficient mice suggest a role for this metabolic sensor in early stages of the disease.What is "Hyper" in the ALS Hypermetabolism?Rilmenidine promotes MTOR-independent autophagy in the mutant SOD1 mouse model of amyotrophic lateral sclerosis without slowing disease progression.Effects of diet on adenosine monophosphate-activated protein kinase activity and disease progression in an amyotrophic lateral sclerosis model.Metabolic Reprogramming in Amyotrophic Lateral Sclerosis.The D2 Dopamine Receptor Interferes With the Protective Effect of the A2A Adenosine Receptor on TDP-43 Mislocalization in Experimental Models of Motor Neuron Degeneration.Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1 Transgenic Mice
P2860
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P2860
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
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2014 nî lūn-bûn
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2014 թուականի Մարտին հրատարակուած գիտական յօդուած
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2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
@ast
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
@en
type
label
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
@ast
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
@en
prefLabel
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
@ast
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
@en
P2093
P2860
P50
P1433
P1476
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models
@en
P2093
Malcolm K Horne
Nirma D Perera
Rebecca K Sheean
P2860
P304
P356
10.1371/JOURNAL.PONE.0090449
P407
P577
2014-03-04T00:00:00Z