Kinetics and mechanism of deoxyhemoglobin S gelation: a new approach to understanding sickle cell disease
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Sickle hemoglobin gelation. Reaction order and critical nucleus sizeEnvironmental determinants of severity in sickle cell diseasePluripotent stem cells in research and treatment of hemoglobinopathiesFibrillogenesis of huntingtin and other glutamine containing proteinsDynamic deformability of sickle red blood cells in microphysiological flow.The Structure of the Cataract-Causing P23T Mutant of Human γD-Crystallin Exhibits Distinctive Local Conformational and Dynamic Changes † , ‡Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell diseaseL-arginine hydrochloride increases the solubility of folded and unfolded recombinant plasminogen activator rPA.Solubility of fluoromethemoglobin S: effect of phosphate and temperature on polymerization.Liquid-liquid separation in solutions of normal and sickle cell hemoglobin.Determination of the transition-state entropy for aggregation suggests how the growth of sickle cell hemoglobin polymers can be slowed.Heterogeneous red blood cell adhesion and deformability in sickle cell disease.Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.The effects of erythrocyte membranes on the nucleation of sickle hemoglobinKinetics of increased deformability of deoxygenated sickle cells upon oxygenation.Treating sickle cell disease by targeting HbS polymerizationFree energy of sickling: A simulation analysis.Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths.Spontaneous generation of mammalian prionsTheoretical description of the spatial dependence of sickle hemoglobin polymerization.Sickle hemoglobin polymer melting in high concentration phosphate buffer.Understanding the shape of sickled red cellsKinetic studies on photolysis-induced gelation of sickle cell hemoglobin suggest a new mechanismThe flow of sickle-cell blood in the capillaries.Saturation transfer electron paramagnetic resonance detection of sickle hemoglobin aggregation during deoxygenationKinetics of domain formation by sickle hemoglobin polymersEffects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17.Sickling times of individual erythrocytes at zero Po2.Kinetics of amyloid aggregation: a study of the GNNQQNY prion sequence.Kinetics of nucleation-controlled polymerization. A perturbation treatment for use with a secondary pathway.Concurrent sickle cell anemia and alpha-thalassemia. Effect on pathological properties of sickle erythrocytesAlpha thalassemia changes erythrocyte heterogeneity in sickle cell disease.Crucial role of nonspecific interactions in amyloid nucleation.Unlocked concanavalin A forms amyloid-like fibrils from coagulation of long-lived "crinkled" intermediates.Profile of William A. EatonThermodynamic studies of polymerization of deoxygenated sickle cell hemoglobin.Supersaturation in sickle cell hemoglobin solutions.Inhibition of erythrocyte sickling by cystamine, a thiol reagent.Electron microscopy of fibers and discs of hemoglobin S having sixfold symmetry.Pharmacotherapy in sickle cell disease--state of the art and future prospects
P2860
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P2860
Kinetics and mechanism of deoxyhemoglobin S gelation: a new approach to understanding sickle cell disease
description
1974 nî lūn-bûn
@nan
1974 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1974 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1974年の論文
@ja
1974年論文
@yue
1974年論文
@zh-hant
1974年論文
@zh-hk
1974年論文
@zh-mo
1974年論文
@zh-tw
1974年论文
@wuu
name
Kinetics and mechanism of deox ...... erstanding sickle cell disease
@ast
Kinetics and mechanism of deox ...... erstanding sickle cell disease
@en
type
label
Kinetics and mechanism of deox ...... erstanding sickle cell disease
@ast
Kinetics and mechanism of deox ...... erstanding sickle cell disease
@en
prefLabel
Kinetics and mechanism of deox ...... erstanding sickle cell disease
@ast
Kinetics and mechanism of deox ...... erstanding sickle cell disease
@en
P2093
P2860
P356
P1476
Kinetics and mechanism of deox ...... erstanding sickle cell disease
@en
P2093
P2860
P304
P356
10.1073/PNAS.71.12.4864
P407
P577
1974-12-01T00:00:00Z