Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis - Wikidata - wikimedia - TriplyDB

Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

http://www.wikidata.org/entity/Q35120235

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Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate The tuberculosis prodrug isoniazid bound to activating peroxidases In vitro antimycobacterial activities of 2'-monosubstituted isonicotinohydrazides and their cyanoborane adducts.Analysis of ahpC gene mutations in isoniazid-resistant clinical isolates of Mycobacterium tuberculosis Overexpression, purification, and characterization of the catalase-peroxidase KatG from Mycobacterium tuberculosis Crystal structure of Mycobacterium tuberculosis catalase-peroxidase Novel selection for isoniazid (INH) resistance genes supports a role for NAD+-binding proteins in mycobacterial INH resistance Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: evaluation of A-ring-modified diphenyl ethers as high-affinity InhA inhibitors Molecular analysis of isoniazid-resistant Mycobacterium tuberculosis isolates from England and Wales reveals the phylogenetic significance of the ahpC -46A polymorphism Radiosynthesis and bioimaging of the tuberculosis chemotherapeutics isoniazid, rifampicin and pyrazinamide in baboons Isoniazid-resistance conferring mutations in Mycobacterium tuberculosis KatG: catalase, peroxidase, and INH-NADH adduct formation activities The susceptibility of Mycobacterium tuberculosis to isoniazid and the Arg-->Leu mutation at codon 463 of katG are not associated.Genetic methods for assessing antimicrobial resistance.Contribution of kasA analysis to detection of isoniazid-resistant Mycobacterium tuberculosis in Singapore.Genotypic analysis of Mycobacterium tuberculosis in two distinct populations using molecular beacons: implications for rapid susceptibility testing.Novel mutations in ndh in isoniazid-resistant Mycobacterium tuberculosis isolates.ethA, inhA, and katG loci of ethionamide-resistant clinical Mycobacterium tuberculosis isolates Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient Exploring the structure and function of the mycobacterial KatG protein using trans-dominant mutants.Population genetics study of isoniazid resistance mutations and evolution of multidrug-resistant Mycobacterium tuberculosis.katG mutations in isoniazid-resistant Mycobacterium tuberculosis isolates recovered from Finnish patients.Molecular analysis of katG gene mutations in strains of Mycobacterium tuberculosis complex from Africa.Effects of overexpression of the alkyl hydroperoxide reductase AhpC on the virulence and isoniazid resistance of Mycobacterium tuberculosis.Novel katG mutations causing isoniazid resistance in clinical M. tuberculosis isolates.Genotypic Analysis of Genes Associated with Independent Resistance and Cross-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Clinical Isolates.Upregulation of the phthiocerol dimycocerosate biosynthetic pathway by rifampin-resistant, rpoB mutant Mycobacterium tuberculosis Genotypic assessment of isoniazid and rifampin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level.Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid Characterization of the MSMEG_2631 gene (mmp) encoding a multidrug and toxic compound extrusion (MATE) family protein in Mycobacterium smegmatis and exploration of its polyspecific nature using biolog phenotype microarray.Multidrug-resistant Mycobacterium tuberculosis: molecular perspectives.Contribution of dfrA and inhA mutations to the detection of isoniazid-resistant Mycobacterium tuberculosis isolates Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.Genotypic and phenotypic characteristics of tunisian isoniazid-resistant Mycobacterium tuberculosis strains.Mutations in the rpoB and katG genes leading to drug resistance in Mycobacterium tuberculosis in Latvia.Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosis.katGI and katGII encode two different catalases-peroxidases in Mycobacterium fortuitum.Revisiting the mutant prevention concentration to guide dosing in childhood tuberculosis.In vitro inhibition of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA by isoniazid.Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis.

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P2860

Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

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Characterization of the katG a ...... of Mycobacterium tuberculosis

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Bai GH

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Morris SL

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P2860

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis

Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis

The emergence of drug-resistant tuberculosis in New York City

An outbreak of tuberculosis caused by multiple-drug-resistant tubercle bacilli among patients with HIV infection

Tuberculosis: commentary on a reemergent killer

The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Genetic systems for mycobacteria

Immunological characterization of recombinant antigens isolated from a Mycobacterium avium lambda gt11 expression library by using monoclonal antibody probes.

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