High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.
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High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring.High Dietary Folate in Mice Alters Immune Response and Reduces Survival after Malarial Infection.High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphismMaternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newbornsExcess Folic Acid Increases Lipid Storage, Weight Gain, and Adipose Tissue Inflammation in High Fat Diet-Fed RatsMaternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy.The antihypertensive MTHFR gene polymorphism rs17367504-G is a possible novel protective locus for preeclampsia.Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation.Murine diet/tissue and human brain tumorigenesis alter Mthfr/MTHFR 5'-end methylation.The adverse effects of an excessive folic acid intake.1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver.Unmetabolized Folic Acid, Tetrahydrofolate, and Colorectal Adenoma Risk.Vitamins Associated with Brain Aging, Mild Cognitive Impairment, and Alzheimer Disease: Biomarkers, Epidemiological and Experimental Evidence, Plausible Mechanisms, and Knowledge Gaps.Maternal Multivitamin Intake, Plasma Folate and Vitamin B12 Levels and Autism Spectrum Disorder Risk in Offspring.Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.The role of the folate pathway in pancreatic cancer risk.Unintended consequences of inhibiting dihydrofolate reductase through folic acid supplementation: inattentive-type attention deficit hyperactivity disorder and ASD connections.Responses of bovine early embryos to S-adenosyl methionine supplementation in culture.Testicular MTHFR deficiency may explain sperm DNA hypomethylation associated with high dose folic acid supplementation.Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects.The association between MTHFR gene polymorphisms (C677T, A1298C) and oral squamous cell carcinoma: A systematic review and meta-analysisAssociations of the MTHFR rs1801133 polymorphism with coronary artery disease and lipid levels: a systematic review and updated meta-analysis
P2860
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P2860
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.
description
2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
High folic acid consumption le ...... ism, and liver injury in mice.
@ast
High folic acid consumption le ...... ism, and liver injury in mice.
@en
type
label
High folic acid consumption le ...... ism, and liver injury in mice.
@ast
High folic acid consumption le ...... ism, and liver injury in mice.
@en
prefLabel
High folic acid consumption le ...... ism, and liver injury in mice.
@ast
High folic acid consumption le ...... ism, and liver injury in mice.
@en
P2093
P2860
P50
P356
P1476
High folic acid consumption le ...... lism, and liver injury in mice
@en
P2093
Karen E Christensen
Kit-Yi Leung
Leonie G Mikael
Liyuan Deng
Marie A Caudill
Nancy Lévesque
Olga V Malysheva
P2860
P304
P356
10.3945/AJCN.114.086603
P407
P577
2015-01-07T00:00:00Z