Combinations of R207910 with drugs used to treat multidrug-resistant tuberculosis have the potential to shorten treatment duration.
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TMC207 for treatment of people with pulmonary tuberculosisTMC207: the first compound of a new class of potent anti-tuberculosis drugsRecent advances in the diagnosis and treatment of childhood tuberculosisBedaquiline for the treatment of multidrug-resistant tuberculosis: great promise or disappointment?Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthaseSterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosisSterilizing Activity of Fully Oral Intermittent Regimens against Mycobacterium Ulcerans Infection in MiceBedaquiline as part of combination therapy in adults with pulmonary multi-drug resistant tuberculosis.Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimensA Review of the Evidence for Using Bedaquiline (TMC207) to Treat Multi-Drug Resistant TuberculosisNew drugs to treat multidrug-resistant tuberculosis: the case for bedaquilineBactericidal potencies of new regimens are not predictive of their sterilizing potencies in a murine model of tuberculosis.New approaches in the diagnosis and treatment of latent tuberculosis infectionActivities of TMC207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs.Contribution of the nitroimidazoles PA-824 and TBA-354 to the activity of novel regimens in murine models of tuberculosis.Short-course chemotherapy with TMC207 and rifapentine in a murine model of latent tuberculosis infection.Sterilizing activity of novel TMC207- and PA-824-containing regimens in a murine model of tuberculosisMycobacterium indicus pranii as stand-alone or adjunct immunotherapeutic in treatment of experimental animal tuberculosis.Synergistic activity of R207910 combined with pyrazinamide against murine tuberculosisPharmacokinetics and pharmacodynamics of TMC207 and its N-desmethyl metabolite in a murine model of tuberculosis.Safety, tolerability, and pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS Clinical Trials Group Study A5267.Sterilizing activities of novel combinations lacking first- and second-line drugs in a murine model of tuberculosis.Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis.Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis.New drugs and regimens for treatment of TB.Impact of the interaction of R207910 with rifampin on the treatment of tuberculosis studied in the mouse model.ATP synthase and the actions of inhibitors utilized to study its roles in human health, disease, and other scientific areas.Model-based estimates of the effects of efavirenz on bedaquiline pharmacokinetics and suggested dose adjustments for patients coinfected with HIV and tuberculosis.The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target.Impact of fluoroquinolone resistance on bactericidal and sterilizing activity of a moxifloxacin-containing regimen in murine tuberculosis.New drugs and vaccines for drug-resistant Mycobacterium tuberculosis infections.ATP synthase inhibition of Mycobacterium avium is not bactericidal.Antimycobacterial drugs currently in Phase II clinical trials and preclinical phase for tuberculosis treatment.Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis.Bedaquiline for the treatment of drug-resistant tuberculosis.Diarylquinolines, synthesis pathways and quantitative structure--activity relationship studies leading to the discovery of TMC207.Prevention of drug carryover effects in studies assessing antimycobacterial efficacy of TMC207.Treatment of multidrug-resistant and extensively drug-resistant tuberculosis: current status and future prospects.Compassionate use of bedaquiline for the treatment of multidrug-resistant and extensively drug-resistant tuberculosis: interim analysis of a French cohort.
P2860
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P2860
Combinations of R207910 with drugs used to treat multidrug-resistant tuberculosis have the potential to shorten treatment duration.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Combinations of R207910 with d ...... to shorten treatment duration.
@ast
Combinations of R207910 with d ...... to shorten treatment duration.
@en
type
label
Combinations of R207910 with d ...... to shorten treatment duration.
@ast
Combinations of R207910 with d ...... to shorten treatment duration.
@en
prefLabel
Combinations of R207910 with d ...... to shorten treatment duration.
@ast
Combinations of R207910 with d ...... to shorten treatment duration.
@en
P2093
P2860
P356
P1476
Combinations of R207910 with d ...... to shorten treatment duration.
@en
P2093
Aurélie Chauffour
Chantal Truffot-Pernot
Koen Andries
Nacer Lounis
Vincent Jarlier
P2860
P304
P356
10.1128/AAC.00766-06
P407
P577
2006-09-05T00:00:00Z