Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity. - Wikidata - wikimedia - TriplyDB

Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity.

Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity.

http://www.wikidata.org/entity/Q35127842

about

Thrombospondin 2 inhibits microvascular endothelial cell proliferation by a caspase-independent mechanism.Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism.Tendon development and musculoskeletal assembly: emerging roles for the extracellular matrix Molecular Characterization of Macrophage-Biomaterial Interactions Biomaterials as carrier, barrier and reactor for cell-based regenerative medicine Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity Control of in vivo microvessel ingrowth by modulation of biomaterial local architecture and chemistry Delineation of candidate genes responsible for structural brain abnormalities in patients with terminal deletions of chromosome 6q27 Matricellular proteins and biomaterials.Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice.Matricellular proteins as modulators of cell-matrix interactions: adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2.Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function.Cervical softening during pregnancy: regulated changes in collagen cross-linking and composition of matricellular proteins in the mouse.Long-term gene therapy with thrombospondin 2 inhibits TGF-β activation, inflammation and angiogenesis in chronic allograft nephropathy Matricellular homologs in the foreign body response: hevin suppresses inflammation, but hevin and SPARC together diminish angiogenesis.Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis.The CC chemokine ligand, CCL2/MCP1, participates in macrophage fusion and foreign body giant cell formation.The thrombospondins.Revisiting the matricellular concept.Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2 Thrombospondin-2 Expression During Retinal Vascular Development and Neovascularization.Profiles of carbohydrate ligands associated with adsorbed proteins on self-assembled monolayers of defined chemistries.Bioactive nanofibers enable the identification of thrombospondin 2 as a key player in enamel regeneration.Manipulating angiogenesis in medicine.Altered extracellular matrix remodeling and angiogenesis in sponge granulomas of thrombospondin 2-null mice Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials.Role of plasma fibronectin in the foreign body response to biomaterials Lack of thrombospondin-2 reduces fibrosis and increases vascularity around cardiac cell grafts.Matricellular proteins in drug delivery: Therapeutic targets, active agents, and therapeutic localization Extracellular matrix-based biomaterial scaffolds and the host response.Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis.Inadequate Processing of Decellularized Dermal Matrix Reduces Cell Viability In Vitro and Increases Apoptosis and Acute Inflammation In Vivo.Macrophage fusion, giant cell formation, and the foreign body response require matrix metalloproteinase 9.Enhanced angiogenesis and reduced contraction in thrombospondin-2-null wounds is associated with increased levels of matrix metalloproteinases-2 and -9, and soluble VEGF.Thrombospondin 2-null mice display an altered brain foreign body response to polyvinyl alcohol sponge implants Gene silencing in human aortic smooth muscle cells induced by PEI-siRNA complexes released from dip-coated electrospun poly(ethylene terephthalate) grafts.The role of thrombospondins in wound healing, ischemia, and the foreign body reaction.Thrombospondin-2 overexpression in the skin of transgenic mice reduces the susceptibility to chemically induced multistep skin carcinogenesis Biomimetic coatings for bone tissue engineering of critical-sized defects Thrombospondin-2 and extracellular matrix assembly.

P2860

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P2860

Mice that lack the angiogenesis inhibitor, thrombospondin 2, mount an altered foreign body reaction characterized by increased vascularity.

http://www.wikidata.org/entity/Q35127842

description

1999 nî lūn-bûn

@nan

1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

1999年の論文

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1999年論文

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1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

name

Mice that lack the angiogenesi ...... ized by increased vascularity.

@ast

Mice that lack the angiogenesi ...... ized by increased vascularity.

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type

label

Mice that lack the angiogenesi ...... ized by increased vascularity.

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Mice that lack the angiogenesi ...... ized by increased vascularity.

@en

prefLabel

Mice that lack the angiogenesi ...... ized by increased vascularity.

@ast

Mice that lack the angiogenesi ...... ized by increased vascularity.

@en

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Mice that lack the angiogenesi ...... ized by increased vascularity.

@en

P2093

A S Hoffman

http://www.w3.org/2001/XMLSchema#string

B D Ratner

http://www.w3.org/2001/XMLSchema#string

K J Leach

http://www.w3.org/2001/XMLSchema#string

P Bornstein

http://www.w3.org/2001/XMLSchema#string

T R Kyriakides

http://www.w3.org/2001/XMLSchema#string

P2860

Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

Inflammatory responses to biomaterials.

New ideas in biomaterials science--a path to engineered biomaterials.

The effect of a subcutaneous silicone rubber implant with shallow surface microgrooves on the surrounding tissues in rabbits.

Molecular determinants of acute inflammatory responses to biomaterials

A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1.

Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia.

Cellular enzyme activity at the polymer-tissue interface: a review.

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4449-4454

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scholarly article

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10.1073/PNAS.96.8.4449

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8

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96

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24448083

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10200282

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16352

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