Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer. - Wikidata - wikimedia - TriplyDB

Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.

Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.

http://www.wikidata.org/entity/Q35127916

about

The biological complexity of RKIP signaling in human cancers Reduced RKIP expression levels are associated with frequent non-small cell lung cancer metastasis and STAT3 phosphorylation and activation.Molecular regulation of bone marrow metastasis in prostate and breast cancer Protein kinase C-mediated phosphorylation of RKIP regulates inhibition of Na-alanine cotransport by leukotriene D(4) in intestinal epithelial cells.RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13.Reduction of RKIP expression promotes nasopharyngeal carcinoma invasion and metastasis by activating Stat3 signaling.Integrated network model provides new insights into castration-resistant prostate cancer Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple-negative breast cancer SUM 159 cells.Reduced RKIP enhances nasopharyngeal carcinoma radioresistance by increasing ERK and AKT activity.RKIP-mediated chemo-immunosensitization of resistant cancer cells via disruption of the NF-κB/Snail/YY1/RKIP resistance-driver loop Raf kinase inhibitor protein (RKIP) inhibits the cell migration and invasion in human glioma cell lines in vitro.Understanding perspectives of signalling mechanisms regulating PEBP1 function.Raf kinase inhibitor protein (RKIP) deficiency decreases latency of tumorigenesis and increases metastasis in a murine genetic model of prostate cancer.Investigational serine/threonine kinase inhibitors against prostate cancer metastases.Crosstalks between Raf-kinase inhibitor protein and cancer stem cell transcription factors (Oct4, KLF4, Sox2, Nanog).Overexpression of RKIP and its cross-talk with several regulatory gene products in multiple myeloma.Raf kinase inhibitor protein regulates oxygen-glucose deprivation-induced PC12 cells apoptosis through the NF-κB and ERK pathways.Metastasis suppressors: functional pathways.MrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly.Raf Kinase Inhibitor Protein Attenuates Ischemic-Induced Microglia Cell Apoptosis and Activation Through NF-κB Pathway.RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact Targeting Raf Kinase Inhibitory Protein Regulation and Function

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Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.

http://www.wikidata.org/entity/Q35127916

description

2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Raf kinase inhibitor protein ( ...... in breast and prostate cancer.

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Raf kinase inhibitor protein ( ...... in breast and prostate cancer.

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Raf kinase inhibitor protein ( ...... in breast and prostate cancer.

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Raf kinase inhibitor protein ( ...... in breast and prostate cancer.

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Benjamin Bonavida

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Devasis Chatterjee

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Eugene Chin

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Kam C Yeung

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Kate Brilliant

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MeiLi Duan

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Saad Yousuf

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Sam Cross-Knorr

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Theresa LaValle

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P2860

Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation

Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells

Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines.

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis

Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

The STATs of cancer--new molecular targets come of age

Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells.

The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus.

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