Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury.
about
How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionHeavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of AntioxidantsThe organic anion transporter (OAT) family: a systems biology perspectiveOrganic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubuleRelationships between the renal handling of DMPS and DMSA and the renal handling of mercuryGender related differences in kidney injury induced by mercuryHandling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in miceRenal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease.What do drug transporters really do?Kidney versus Liver Specification of SLC and ABC Drug Transporters, Tight Junction Molecules, and Biomarkers.Hepatocyte nuclear factors 4α and 1α regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters.Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity.Progress in the development of animal models of acute kidney injury and its impact on drug discovery.The drug transporter OAT3 (SLC22A8) regulates endogenous metabolite flow through the gut-liver-kidney axis.Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and SolutesTranscriptional regulation of human organic anion transporter 1 by B-cell CLL/lymphoma 6.Xenobiotic transporters and kidney injury.An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network.Expression of basolateral organic anion and cation transporters in experimental cadmium nephrotoxicity in rat kidney.From the Cover: Identification of Natural Products as Inhibitors of Human Organic Anion Transporters (OAT1 and OAT3) and Their Protective Effect on Mercury-Induced Toxicity.Beyond drug-drug interactions: effects of transporter inhibition on endobiotics, nutrients and toxins.Renal expression and function of oat1 and oat3 in rats with vascular calcification.A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease.
P2860
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P2860
Deletion of multispecific organic anion transporter Oat1/Slc22a6 protects against mercury-induced kidney injury.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Deletion of multispecific orga ...... mercury-induced kidney injury.
@ast
Deletion of multispecific orga ...... mercury-induced kidney injury.
@en
type
label
Deletion of multispecific orga ...... mercury-induced kidney injury.
@ast
Deletion of multispecific orga ...... mercury-induced kidney injury.
@en
prefLabel
Deletion of multispecific orga ...... mercury-induced kidney injury.
@ast
Deletion of multispecific orga ...... mercury-induced kidney injury.
@en
P2093
P2860
P356
P1476
Deletion of multispecific orga ...... mercury-induced kidney injury.
@en
P2093
Adriana M Torres
Ankur V Dnyanmote
Kevin T Bush
Sanjay K Nigam
P2860
P304
26391-26395
P356
10.1074/JBC.M111.249292
P407
P577
2011-06-07T00:00:00Z