A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
about
Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processesPhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsNeutral sphingomyelinase 2 deficiency is associated with lung anomalies similar to emphysemaNeutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscleCholine kinase beta is required for normal endochondral bone formationCalcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDLNeutral sphingomyelinase 2 deficiency increases hyaluronan synthesis by up-regulation of Hyaluronan synthase 2 through decreased ceramide production and activation of AktHMGB1 Induces Secretion of Matrix Vesicles by Macrophages to Enhance Ectopic Mineralization.Evidence for coordination of lysosomal (ASMase) and plasma membrane (NSMase2) forms of sphingomyelinase from mutant mice.Histomorphometric and microarchitectural analyses using the 2 mm bone marrow trephine in metastatic breast cancer patients-preliminary resultsComparison of bone tissue properties in mouse models with collagenous and non-collagenous genetic mutations using FTIRI.ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation.Smpd3 Expression in both Chondrocytes and Osteoblasts Is Required for Normal Endochondral Bone Development.The Expression of PHOSPHO1, nSMase2 and TNAP is Coordinately Regulated by Continuous PTH Exposure in Mineralising Osteoblast Cultures.The roles of neutral sphingomyelinases in neurological pathologies.Tooth dentin defects reflect genetic disorders affecting bone mineralization.Sphingolipid metabolism and neutral sphingomyelinases.Sphingolipid metabolism and its role in the skeletal tissues.Sphingolipids in the DNA damage response.Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanismSphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells.Emerging roles for vascular smooth muscle cell exosomes in calcification and coagulation.Local regulation of tooth mineralization by sphingomyelin phosphodiesterase 3.Dietary vitamin D during pregnancy has dose-dependent effects on long bone density and architecture in guinea pig offspring but not the sows.Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation.Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide.
P2860
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P2860
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
@ast
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
@en
type
label
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
@ast
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
@en
prefLabel
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
@ast
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
@en
P2093
P2860
P356
P1476
A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.
@en
P2093
Christophe Poirier
Christopher J Clarke
Jingjing Li
Marc D McKee
Monzur Murshed
Nicholas Wang
Yusuf A Hannun
Zohreh Khavandgar
P2860
P304
P356
10.1083/JCB.201102051
P407
P577
2011-07-01T00:00:00Z