Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells - Wikidata - wikimedia - TriplyDB

Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells

Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells

http://www.wikidata.org/entity/Q35131712

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Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner.N-MYC regulates focal adhesion kinase expression in human neuroblastoma.Inhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell lines Analyses of merlin/NF2 connection to FAK inhibitor responsiveness in serous ovarian cancer Focal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer.FAK deletion promotes p53-mediated induction of p21, DNA-damage responses and radio-resistance in advanced squamous cancer cells.Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles.MDR1 siRNA loaded hyaluronic acid-based CD44 targeted nanoparticle systems circumvent paclitaxel resistance in ovarian cancer.Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines.Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.Inhibition of FAK and VEGFR-3 binding decreases tumorigenicity in neuroblastoma.Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer.Encapsulation of docetaxel in oily core polyester nanocapsules intended for breast cancer therapy Up-regulation of CD44 in the development of metastasis, recurrence and drug resistance of ovarian cancer.Expression and clinical significance of focal adhesion kinase and adrenomedullin in epithelial ovarian cancer.Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival.Erythropoietin Stimulates Tumor Growth via EphB4.The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma Focal adhesion kinase is a phospho-regulated repressor of Rac and proliferation in human endothelial cells.Modulation of response to tumor therapies by the extracellular matrix.Quinacrine promotes autophagic cell death and chemosensitivity in ovarian cancer and attenuates tumor growth.Enhancing chemotherapy response with sustained EphA2 silencing using multistage vector delivery.Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression.Focal adhesion kinase: a promising target for anticancer therapy.Moving beyond VEGF for anti-angiogenesis strategies in gynecologic cancer A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth.Role of focal adhesion kinase in regulating YB-1-mediated paclitaxel resistance in ovarian cancer.Inhibition of the focal adhesion kinase and vascular endothelial growth factor receptor-3 interaction leads to decreased survival in human neuroblastoma cell lines.A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice.Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines.Dual targeting of EphA2 and FAK in ovarian carcinoma.Therapeutic Targeting of ATP7B in Ovarian Carcinoma.MiR-138 and MiR-135 directly target focal adhesion kinase, inhibit cell invasion, and increase sensitivity to chemotherapy in cancer cells.Ambivalent role of pFAK-Y397 in serous ovarian cancer--a study of the OVCAD consortium.The dual kinase complex FAK-Src as a promising therapeutic target in cancer Targeting non-receptor tyrosine kinases using small molecule inhibitors: an overview of recent advances.Circulating peptidome to indicate the tumor-resident proteolysis.Disruption of laminin-integrin-CD151-focal adhesion kinase axis sensitizes breast cancer cells to ErbB2 antagonists.

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P2860

Focal adhesion kinase silencing augments docetaxel-mediated apoptosis in ovarian cancer cells

http://www.wikidata.org/entity/Q35131712

description

2005 nî lūn-bûn

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2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Focal adhesion kinase silencin ...... ptosis in ovarian cancer cells

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Focal adhesion kinase silencin ...... ptosis in ovarian cancer cells

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Focal adhesion kinase silencin ...... ptosis in ovarian cancer cells

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Focal adhesion kinase silencin ...... ptosis in ovarian cancer cells

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Focal adhesion kinase silencin ...... ptosis in ovarian cancer cells

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Focal adhesion kinase silencin ...... ptosis in ovarian cancer cells

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Clinical Cancer Research

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Focal adhesion kinase silencin ...... ptosis in ovarian cancer cells

@en

P2093

Anil K Sood

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Charles N Landen

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Dominic Fan

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Gina M Nelkin

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Jyotsnabaran Halder

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Michael D Schaller

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Nicholas B Jennings

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Rosemarie Schmandt

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Susan K Lutgendorf

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Yang Li

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P2860

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Differential regulation of cell motility and invasion by FAK

Integrins: versatility, modulation, and signaling in cell adhesion

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

FAK integrates growth-factor and integrin signals to promote cell migration

Signaling through focal adhesion kinase

Biochemical signals and biological responses elicited by the focal adhesion kinase

Docetaxel-carboplatin as first line chemotherapy for epithelial ovarian cancer

Cleavage of focal adhesion kinase by caspases during apoptosis

Caspases: enemies within

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8829-8836

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10.1158/1078-0432.CCR-05-1728

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P433

24 Pt 1

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11

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2005-12-01T00:00:00Z

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16361572

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