Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders
about
Order, Disorder, and Everything in BetweenProteomics in Traditional Chinese Medicine with an Emphasis on Alzheimer's DiseaseAcetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.Impaired neurodevelopment by the low complexity domain of CPEB4 reveals a convergent pathway with neurodegeneration.Tau Biology and Tau-Directed Therapies for Alzheimer's DiseaseIntrinsic disorder in proteins involved in amyotrophic lateral sclerosis.Bayesian inference of protein ensembles from SAXS data.Proteins with Intrinsically Disordered Domains Are Preferentially Recruited to Polyglutamine Aggregates.Small Molecules Detected by Second-Harmonic Generation Modulate the Conformation of Monomeric α-Synuclein and Reduce Its Aggregation in CellsRegion-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes.Structural disorder of monomeric α-synuclein persists in mammalian cells.Microtubule dynamics and the neurodegenerative triad of Alzheimer's disease: The hidden connection.Glycation induces conformational changes in the amyloid-β peptide and enhances its aggregation propensity: molecular insights.Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells.Characterization of Amyloid Cores in Prion Domains.Transcription factor clusters regulate genes in eukaryotic cells.The Rho Termination Factor of Clostridium botulinum Contains a Prion-Like Domain with a Highly Amyloidogenic Core.Oligomerization of the microtubule-associated protein tau is mediated by its N-terminal sequences: implications for normal and pathological tau action.Exploring disorder in the human charged biased proteins.Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.Neuronal pathophysiology featuring PrPC and its control over Ca2+ metabolism.Intrinsic Disorder in Proteins with Pathogenic Repeat Expansions.Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration.Tau Filaments and the Development of Positron Emission Tomography Tracers.Structural evaluations of tau protein conformation: methodologies and approaches.Deciphering the dark proteome of Chikungunya virus.Annexins A2 and A6 interact with the extreme N-terminus of tau and thereby contribute to tau's axonal localization.Sirtuins in Neuroendocrine Regulation and Neurological DiseasesIdentifying weak interdomain interactions that stabilize the supertertiary structure of the N-terminal tandem PDZ domains of PSD-95Transcription factors in eukaryotic cells can functionally regulate gene expression by acting in oligomeric assemblies formed from an intrinsically disordered protein phase transition enabled by molecular crowding
P2860
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P2860
Intrinsically disordered proteins and their (disordered) proteomes in neurodegenerative disorders
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Intrinsically disordered prote ...... in neurodegenerative disorders
@ast
Intrinsically disordered prote ...... in neurodegenerative disorders
@en
type
label
Intrinsically disordered prote ...... in neurodegenerative disorders
@ast
Intrinsically disordered prote ...... in neurodegenerative disorders
@en
prefLabel
Intrinsically disordered prote ...... in neurodegenerative disorders
@ast
Intrinsically disordered prote ...... in neurodegenerative disorders
@en
P2860
P356
P1476
Intrinsically disordered prote ...... in neurodegenerative disorders
@en
P2860
P356
10.3389/FNAGI.2015.00018
P577
2015-03-02T00:00:00Z