Stochastic receptor expression determines cell fate upon interferon treatment.
about
IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damageInterplay between gene expression noise and regulatory network architectureReceptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingStructural Linkage between Ligand Discrimination and Receptor Activation by Type I InterferonsStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potencyDisease-promoting effects of type I interferons in viral, bacterial, and coinfectionsInterferons and viruses: an evolutionary arms race of molecular interactionsCytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes.Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response.Live cell micropatterning reveals the dynamics of signaling complexes at the plasma membraneA structured population modeling framework for quantifying and predicting gene expression noise in flow cytometry data.A new efficient approach to fit stochastic models on the basis of high-throughput experimental data using a model of IRF7 gene expression as case study.Interferons and their stimulated genes in the tumor microenvironmentStochastic expression of the interferon-β gene.Enhanced in vivo efficacy of a type I interferon superagonist with extended plasma half-life in a mouse model of multiple sclerosisMultifaceted activities of type I interferon are revealed by a receptor antagonist.Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness.Understanding cytokine and growth factor receptor activation mechanisms.Haploinsufficiency at the human IFNGR2 locus contributes to mycobacterial disease.Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPaseBridging the species divide: transgenic mice humanized for type-I interferon response.Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury.Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents.The interferons and their receptors--distribution and regulation.Hope and fear for interferon: the receptor-centric outlook on the future of interferon therapy.Interferons in the central nervous system: a few instruments play many tunes.Type I Interferon Signaling Is Decoupled from Specific Receptor Orientation through Lenient Requirements of the Transmembrane Domain.IFNA2: The prototypic human alpha interferon.Quantitative profiling of innate immune activation by viral infection in single cells.Quantifying enzyme activity in living cells.Fine Tuning of a Type 1 Interferon Antagonist.Human pDCs display sex-specific differences in type I interferon subtypes and interferon α/β receptor expression.The molecular basis for differential type I interferon signaling.The Impact of the Interferon/TNF-Related Apoptosis-Inducing Ligand Signaling Axis on Disease Progression in Respiratory Viral Infection and Beyond.Type I interferons induce apoptosis by balancing cFLIP and caspase-8 independent of death ligands.Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.Role of Type I and II Interferons in Colorectal Cancer and Melanoma.Emergent properties of the interferon-signalling network may underlie the success of hepatitis C treatment.A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I Interferon.
P2860
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P2860
Stochastic receptor expression determines cell fate upon interferon treatment.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Stochastic receptor expression determines cell fate upon interferon treatment.
@ast
Stochastic receptor expression determines cell fate upon interferon treatment.
@en
type
label
Stochastic receptor expression determines cell fate upon interferon treatment.
@ast
Stochastic receptor expression determines cell fate upon interferon treatment.
@en
prefLabel
Stochastic receptor expression determines cell fate upon interferon treatment.
@ast
Stochastic receptor expression determines cell fate upon interferon treatment.
@en
P2093
P2860
P356
P1476
Stochastic receptor expression determines cell fate upon interferon treatment.
@en
P2093
Daniel Harari
Doron Levin
Gideon Schreiber
P2860
P304
P356
10.1128/MCB.05251-11
P407
P577
2011-06-20T00:00:00Z