The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia - Wikidata - wikimedia - TriplyDB

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

http://www.wikidata.org/entity/Q35140239

about

Y-chromosomal genes affecting male fertility: A review The complexity of epigenetic diseases An integrative view on sex differences in brain tumors Comprehensive mutation profiling of mucinous gastric carcinoma.Emerging concepts of epigenetic dysregulation in hematological malignancies Childhood acute lymphoblastic leukemia: Integrating genomics into therapy Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia Context Specific and Differential Gene Co-expression Networks via Bayesian Biclustering Non-negligible Occurrence of Errors in Gender Description in Public Data Sets.Epigenetics in normal and malignant hematopoiesis: An overview and update 2017.RBP2 Promotes Adult Acute Lymphoblastic Leukemia by Upregulating BCL2.Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation Derivation of consensus inactivation status for X-linked genes from genome-wide studies Targeting EZH2 and PRC2 dependence as novel anticancer therapy.UTX inhibits EMT-induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1.UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia X-chromosome inactivation and escape.Epigenetic Dysfunction in Turner Syndrome Immune Cells.Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients Pleiotropic Functions of H3K27Me3 Demethylases in Immune Cell Differentiation.Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.Histone Demethylase KDM6A Controls the Mammary Luminal Lineage through Enzyme-Independent Mechanisms.Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias.The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia.Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations Marked for death: targeting epigenetic changes in cancer.MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer.Lysine-specific histone demethylases in normal and malignant hematopoiesis.Epigenetic balance of gene expression by Polycomb and COMPASS families.Histone demethylase Utx regulates differentiation and mineralization in osteoblasts.Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer.H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.Pediatric T-cell acute lymphoblastic leukemia.Genomic characterization of paediatric acute lymphoblastic leukaemia: an opportunity for precision medicine therapeutics.The genetics and molecular biology of T-ALL.Epigenetic regulatory mutations and epigenetic therapy for multiple myeloma.Orchestration of H3K27 methylation: mechanisms and therapeutic implication.Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.Heterochromatin Reduction Correlates with the Increase of the KDM4B and KDM6A Demethylases and the Expression of Pericentromeric DNA during the Acquisition of a Transformed Phenotype.

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The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

http://www.wikidata.org/entity/Q35140239

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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The H3K27me3 demethylase UTX i ...... l acute lymphoblastic leukemia

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Ari M Melnick

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Björn Menten

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Bruce Poppe

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Bruno Verhasselt

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Eric Delabesse

http://www.w3.org/2001/XMLSchema#string

Fang Fang

http://www.w3.org/2001/XMLSchema#string

Filip Matthijssens

http://www.w3.org/2001/XMLSchema#string

Hans-Guido Wendel

http://www.w3.org/2001/XMLSchema#string

Joni Van der Meulen

http://www.w3.org/2001/XMLSchema#string

Kaat Durinck

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P2860

Deletions of PURA, at 5q31, and PURB, at 7p13, in myelodysplastic syndrome and progression to acute myelogenous leukemia

mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia

arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays.

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

DOCK4, a GTPase activator, is disrupted during tumorigenesis

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

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