Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
about
Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndromeSCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cellsSites of instability in the human TCF3 (E2A) gene adopt G-quadruplex DNA structures in vitroG-quadruplex DNA structures can interfere with uracil glycosylase activity in vitro.A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR(-) B cells.Repression of TCF3/E2A contributes to Hodgkin lymphomagenesis.E2A predicts prognosis of colorectal cancer patients and regulates cancer cell growth by targeting miR-320aB-lineage transcription factors and cooperating gene lesions required for leukemia development.Mature T-cell leukemias: Molecular and Clinical Aspects.Sézary syndrome: old enigmas, new targets.Analysis of the IL-31 pathway in Mycosis fungoides and Sézary syndrome.miRNA-214 is related to invasiveness of human non-small cell lung cancer and directly regulates alpha protein kinase 2 expression.The tumour suppressor p53 is frequently nonfunctional in Sézary syndrome.Genomic analyses reveal recurrent mutations in epigenetic modifiers and the JAK-STAT pathway in Sézary syndromeNRAS mutations in cutaneous T cell lymphoma (CTCL) sensitize tumors towards treatment with the multikinase inhibitor Sorafenib.Cell-intrinsic in vivo requirement for the E47-p21 pathway in long-term hematopoietic stem cellsT-cell receptor gene rearrangement analysis of sequential biopsies in cutaneous T-cell lymphomas with the Biomed-2 PCR reveals transient T-cell clones in addition to the tumor clone.Genome-Wide Analysis of Interchromosomal Interaction Probabilities Reveals Chained Translocations and Overrepresentation of Translocation Breakpoints in Genes in a Cutaneous T-Cell Lymphoma Cell Line.
P2860
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P2860
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
@ast
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
@en
type
label
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
@ast
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
@en
prefLabel
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
@ast
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma.
@en
P2093
P2860
P356
P1476
Genomic loss of the putative tumor suppressor gene E2A in human lymphoma
@en
P2093
Anne Steininger
Bernd Dörken
Björn Lamprecht
Chalid Assaf
Claus-Detlev Klemke
Evelin Schrock
Harald Stein
Ioannis Anagnostopoulos
Julia Richter
Karl Köchert
P2860
P304
P356
10.1084/JEM.20101785
P407
P50
P577
2011-07-25T00:00:00Z