Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I). - Wikidata - wikimedia - TriplyDB

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

http://www.wikidata.org/entity/Q35144837

about

PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin Architecture and biogenesis of plus-strand RNA virus replication factories RNA mediated Toll-like receptor stimulation in health and disease mRNA capping: biological functions and applications Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism Structural basis of RNA recognition and activation by innate immune receptor RIG-I Structural Insights into RNA Recognition by RIG-I MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA Ebolavirus VP35 Coats the Backbone of Double-Stranded RNA for Interferon Antagonism Defining the functional determinants for RNA surveillance by RIG-I International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease Influenza virus activation of the interferon system Influenza A(H1N1)pdm09 virus suppresses RIG-I initiated innate antiviral responses in the human lung.Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.A structure-based model of RIG-I activation LGP2 plays a critical role in sensitizing mda-5 to activation by double-stranded RNA RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication Coxsackievirus cloverleaf RNA containing a 5' triphosphate triggers an antiviral response via RIG-I activation RIG-I self-oligomerization is either dispensable or very transient for signal transduction.Activation and evasion of antiviral innate immunity by hepatitis C virus.Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5 Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.Which Way In? The RalF Arf-GEF Orchestrates Rickettsia Host Cell Invasion Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus.Sequence-Specific Modifications Enhance the Broad-Spectrum Antiviral Response Activated by RIG-I Agonists dsRNA-dependent protein kinase PKR and its role in stress, signaling and HCV infection.The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection.A Hierarchical Mechanism of RIG-I Ubiquitination Provides Sensitivity, Robustness and Synergy in Antiviral Immune Responses.ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon Failure of innate and adaptive immune responses in controlling hepatitis C virus infection.Structural insights into RNA recognition and activation of RIG-I-like receptors.Multi-level regulation of cellular recognition of viral dsRNA.Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing.Helicase-mediated changes in RNA structure at the single-molecule level.Sensing microbial RNA in the cytosol.Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5 Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH How RIG-I like receptors activate MAVS.

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Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

http://www.wikidata.org/entity/Q35144837

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Molecular mechanism of signal ...... acid-inducible gene-I (RIG-I).

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Molecular mechanism of signal ...... acid-inducible gene-I (RIG-I).

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Molecular mechanism of signal ...... acid-inducible gene-I (RIG-I).

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Molecular mechanism of signal ...... acid-inducible gene-I (RIG-I).

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Molecular mechanism of signal ...... acid-inducible gene-I (RIG-I).

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Molecular mechanism of signal ...... acid-inducible gene-I (RIG-I).

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P356

JBC.M111.256974

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Journal of Biological Chemistry

P1476

Molecular mechanism of signal ...... acid-inducible gene-I (RIG-I).

@en

P2093

Alexander Dalpke

http://www.w3.org/2001/XMLSchema#string

Christian M Hüber

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Florian Eberle

http://www.w3.org/2001/XMLSchema#string

Norbert Mücke

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Stefan Seitz

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P2860

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Activation of MDA5 requires higher-order RNA structures generated during virus infection

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

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27278-27287

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scholarly article

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10.1074/JBC.M111.256974

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31

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P478

286

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Ralf Bartenschlager

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2011-06-09T00:00:00Z

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21659521

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3149321

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