The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer.
about
The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsSynergistic inhibition of autophagy and neddylation pathways as a novel therapeutic approach for targeting liver cancer.Suppression of glioblastoma by targeting the overactivated protein neddylation pathway.NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent mannerRadiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells.MLN4924 therapy as a novel approach in cancer treatment modalities.The RhoB small GTPase in physiology and disease.The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB.Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy.The Nedd8-activating enzyme inhibitor MLN4924 suppresses colon cancer cell growth triggering autophagyiTRAQ-based analysis of sperm proteome from normozoospermic men achieving the rescue-ICSI pregnancy after the IVF failure
P2860
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P2860
The neddylation-cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer.
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
The neddylation-cullin 2-RBX1 ...... r degradation in liver cancer.
@ast
The neddylation-cullin 2-RBX1 ...... r degradation in liver cancer.
@en
type
label
The neddylation-cullin 2-RBX1 ...... r degradation in liver cancer.
@ast
The neddylation-cullin 2-RBX1 ...... r degradation in liver cancer.
@en
prefLabel
The neddylation-cullin 2-RBX1 ...... r degradation in liver cancer.
@ast
The neddylation-cullin 2-RBX1 ...... r degradation in liver cancer.
@en
P2093
P2860
P356
P1476
The neddylation-cullin 2-RBX1 ...... or degradation in liver cancer
@en
P2093
Dongping Wei
Guangyang Yu
Junfeng Xu
Shengzhong Duan
P2860
P304
P356
10.1074/MCP.M114.045211
P50
P577
2014-12-24T00:00:00Z