Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. - Wikidata - wikimedia - TriplyDB

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice.

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice.

http://www.wikidata.org/entity/Q35152196

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The Potential of Non-Provitamin A Carotenoids for the Prevention and Treatment of Non-Alcoholic Fatty Liver Disease Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver-insights into mechanisms of hepatic steatosis Whole genome transcript profiling of drug induced steatosis in rats reveals a gene signature predictive of outcome Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis.Hematopoietic androgen receptor deficiency promotes visceral fat deposition in male mice without impairing glucose homeostasis.Compared with Powdered Lutein, a Lutein Nanoemulsion Increases Plasma and Liver Lutein, Protects against Hepatic Steatosis, and Affects Lipoprotein Metabolism in Guinea Pigs.Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR-/- and LDLR+/+ mice.Induction of steatohepatitis (NASH) with insulin resistance in wildtype B6 mice by a western-type diet containing soybean oil and cholesterol.Significant Improvement Selected Mediators of Inflammation in Phenotypes of Women with PCOS after Reduction and Low GI Diet Acceleration of biliary cholesterol secretion restores glycemic control and alleviates hypertriglyceridemia in obese db/db mice.High-fat and obesogenic diets: current and future strategies to fight obesity and diabetes.Deletion of serum amyloid A3 improves high fat high sucrose diet-induced adipose tissue inflammation and hyperlipidemia in female mice Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance.Mechanism of the promotion of steatotic HepG2 cell apoptosis by cholesterol Cholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH.Transcriptomic analysis of hepatic responses to testosterone deficiency in miniature pigs fed a high-cholesterol diet.The combination of ezetimibe and ursodiol promotes fecal sterol excretion and reveals a G5G8-independent pathway for cholesterol elimination.PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis The macrophage phagocytic receptor CD36 promotes fibrogenic pathways on removal of apoptotic cells during chronic kidney injury.Do the interactions between glucocorticoids and sex hormones regulate the development of the metabolic syndrome?Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia.The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer High fat plus high cholesterol diet lead to hepatic steatosis in zebrafish larvae: a novel model for screening anti-hepatic steatosis drugs.Metabolically distinct weight loss by 10,12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice.Therapeutic administration of the direct thrombin inhibitor argatroban reduces hepatic inflammation in mice with established fatty liver disease.Inhibition of intestinal cholesterol absorption decreases atherosclerosis but not adipose tissue inflammation Oxidative stress contributes to abnormal glucose metabolism and insulin sensitivity in two hyperlipidemia models Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr⁻/⁻ mice.Plasma lipid profiling of different types of hepatic fibrosis induced by carbon tetrachloride and lomustine in rats Molecular signature of adipose tissue in patients with both non-alcoholic fatty liver disease (NAFLD) and polycystic ovarian syndrome (PCOS).Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice.Açai (Euterpe oleracea Mart.) Upregulates Paraoxonase 1 Gene Expression and Activity with Concomitant Reduction of Hepatic Steatosis in High-Fat Diet-Fed Rats.Beneficial effect of a weight-stable, low-fat/low-saturated fat/low-glycaemic index diet to reduce liver fat in older subjects.Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances.Fatty acid-regulated transcription factors in the liver.Effects of dietary cholesterol and its oxidation products on pathological lesions and cholesterol and lipid oxidation in the rabbit liver.

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Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice.

http://www.wikidata.org/entity/Q35152196

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2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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Dietary cholesterol exacerbate ...... e LDL receptor-deficient mice.

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Dietary cholesterol exacerbate ...... e LDL receptor-deficient mice.

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Dietary cholesterol exacerbate ...... e LDL receptor-deficient mice.

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Dietary cholesterol exacerbate ...... e LDL receptor-deficient mice.

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Dietary cholesterol exacerbate ...... e LDL receptor-deficient mice.

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Journal of Lipid Research

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Dietary cholesterol exacerbate ...... e LDL receptor-deficient mice.

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Alan Chait

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George N Ioannou

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Jinkyu Kim

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Kevin D O'Brien

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Kris V Kowdley

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Leela Goodspeed

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Lixia Zeng

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Matthew M Yeh

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Savitha Subramanian

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Shari Wang

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P2860

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

A simple method for the isolation and purification of total lipides from animal tissues

Obesity is associated with macrophage accumulation in adipose tissue

Serum amyloid A, the major vertebrate acute-phase reactant

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis

Nonalcoholic Fatty Liver Disease: A Feature of the Metabolic Syndrome

Steatohepatitis: a tale of two "hits"?

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

Molecular mediators of hepatic steatosis and liver injury

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10.1194/JLR.M016246

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9

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