Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
about
Genome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyPrecommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.The Spatiotemporal Pattern of Glis3 Expression Indicates a Regulatory Function in Bipotent and Endocrine Progenitors during Early Pancreatic Development and in Beta, PP and Ductal CellsFeedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.Growth Hormone Mediates Its Protective Effect in Hepatic Apoptosis through Hnf6Monogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.Adult human pancreas-derived cells expressing stage-specific embryonic antigen 4 differentiate into Sox9-expressing and Ngn3-expressing pancreatic ducts in vivo.HNF1B-associated clinical phenotypes: the kidney and beyond.The role of hepatocyte nuclear factor 1β in disease and development.Single cell transcriptomic profiling of mouse pancreatic progenitors.Culturing and transcriptome profiling of progenitor-like colonies derived from adult mouse pancreas.Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells.Epigenetics in formation, function, and failure of the endocrine pancreas.Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.Transcription Factor Hepatocyte Nuclear Factor-1β Regulates Renal Cholesterol Metabolism.The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival.HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis.GLIS1-3: emerging roles in reprogramming, stem and progenitor cell differentiation and maintenance.HNF1B, TSPAN8 and NOTCH2 gene polymorphisms in women with gestational diabetes.Cellular and molecular mechanisms coordinating pancreas development.Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.A Novel p.L145Q Mutation in the HNF1B Gene in a Case of Maturity-onset Diabetes of the Young Type 5 (MODY5).Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation.Single-cell analyses of human islet cells reveal de-differentiation signatures.De novo HNF1 homeobox B mutation as a cause for chronic, treatment-resistant hypomagnesaemia.Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid
P2860
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P2860
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
@ast
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
@en
type
label
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
@ast
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
@en
prefLabel
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
@ast
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
@en
P2093
P2860
P356
P1433
P1476
Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
@en
P2093
Claire Heliot
Janel L Kopp
Maike Sander
Matias G De Vas
Silvia Cereghini
P2860
P304
P356
10.1242/DEV.110759
P407
P577
2015-03-01T00:00:00Z