M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss. - Wikidata - wikimedia - TriplyDB

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

http://www.wikidata.org/entity/Q35159009

about

RUNX3, EGR1 and SOX9B form a regulatory cascade required to modulate BMP-signaling during cranial cartilage development in zebrafish Mechanism of stimulation of osteoclastic bone resorption through Gas6/Tyro 3, a receptor tyrosine kinase signaling, in mouse osteoclasts.Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation.Estrogen action on bone marrow osteoclast lineage cells of postmenopausal women in vivo.Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo.Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.An IL-7-dependent rebound in thymic T cell output contributes to the bone loss induced by estrogen deficiency.Krox20/EGR2 deficiency accelerates cell growth and differentiation in the monocytic lineage and decreases bone mass Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand.Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency Osteoclasts lacking Rac2 have defective chemotaxis and resorptive activity.Loss of transcription factor early growth response gene 1 results in impaired endochondral bone repair.IFN-gamma stimulates osteoclast formation and bone loss in vivo via antigen-driven T cell activation.Selective deletion of the membrane-bound colony stimulating factor 1 isoform leads to high bone mass but does not protect against estrogen-deficiency bone loss.Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator.Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation Bone remodeling in post-menopausal osteoporosis.The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration.Targeted overexpression of the two colony-stimulating factor-1 isoforms in osteoblasts differentially affects bone loss in ovariectomized mice Functional characterization of genetic variation in the Frizzled 1 (FZD1) promoter and association with bone phenotypes: more to the LRP5 story?Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B.Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha.Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs.Estrogen prevents bone loss through transforming growth factor beta signaling in T cells.FMS Kinase Inhibitors: Current Status and Future Prospects.IL-34 and CSF-1: similarities and differences.12-O-tetradecanoylphorbol-13-acetate (TPA) inhibits osteoclastogenesis by suppressing RANKL-induced NF-kappaB activation.Macrophages and skeletal health.Osteomacs and Bone Regeneration.Dysregulation of CXCL9 and reduced tumor growth in Egr-1 deficient mice Immune system-related differentially expressed genes, transcription factors and microRNAs in post-menopausal females with osteopenia.Epidermal α6β4 integrin stimulates the influx of immunosuppressive cells during skin tumor promotion Selective deletion of the soluble Colony-Stimulating Factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice.Key Triggers of Osteoclast-Related Diseases and Available Strategies for Targeted Therapies: A Review.EGR1 supports the osteogenic differentiation of dental stem cells.Effect of cigarette smoke inhalation and estrogen deficiency on bone healing around titanium implants: a histometric study in rats.Early growth response gene 1 regulates bone properties in mice.Biglycan deficiency interferes with ovariectomy-induced bone loss.Bone- and cartilage-protective effects of a monoclonal antibody against colony-stimulating factor 1 receptor in experimental arthritis.

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M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

http://www.wikidata.org/entity/Q35159009

description

2000 nî lūn-bûn

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2000 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2000 թվականի մայիսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

@zh-hk

2000年論文

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2000年論文

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2000年论文

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name

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

@ast

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

@en

type

label

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

@ast

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

@en

prefLabel

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

@ast

M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss.

@en

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Journal of Clinical Investigation

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M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss

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M A Gentile

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M C Aisa

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M N Weitzmann

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R Pacifici

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P2860

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

Interleukin-1 receptor antagonist decreases bone loss and bone resorption in ovariectomized rats.

Cloning and tissue-specific expression of mouse macrophage colony-stimulating factor mRNA.

Granulocyte/macrophage colony-stimulating factor and interleukin-3 correct osteopetrosis in mice with osteopetrosis mutation.

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1279-1287

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10.1172/JCI8672

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