CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2. - Wikidata - wikimedia - TriplyDB

CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.

CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.

http://www.wikidata.org/entity/Q35161639

about

Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression A human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFb LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer Crystal structure of human cyclin K, a positive regulator of cyclin-dependent kinase 9 An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer Cyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV Tat Structural insights into the cyclin T1-Tat-TAR RNA transcription activation complex from EIAV Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure–Activity Relationship, and Anticancer Activities Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells Chemical Composition and In Vitro Cytotoxicity of Essential Oils from Leaves and Flowers of Callistemon citrinus from Western Himalayas Up-regulation of P-TEFb by the MEK1-extracellular signal-regulated kinase signaling pathway contributes to stimulated transcription elongation of immediate early genes in neuroendocrine cells Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis Functional characterization of a new member of the Cdk9 family in Aspergillus nidulans.Ubiquitylation of Cdk9 by Skp2 facilitates optimal Tat transactivation.P-TEFb kinase complex phosphorylates histone H1 to regulate expression of cellular and HIV-1 genes.Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73.A transcriptional activator is part of an SCF ubiquitin ligase to control degradation of its cofactors The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex Oncogenic aberrations of cullin-dependent ubiquitin ligases.Use of ATP analogs to inhibit HIV-1 transcription.Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs Direct inhibition of CDK9 blocks HIV-1 replication without preventing T-cell activation in primary human peripheral blood lymphocytes.Cyclin E and SV40 small T antigen cooperate to bypass quiescence and contribute to transformation by activating CDK2 in human fibroblasts.Selective control of gene expression by CDK9 in human cells The emerging picture of CDK9/P-TEFb: more than 20 years of advances since PITALRE.CDK9/cyclin complexes modulate endoderm induction by direct interaction with Mix.3/mixer.Transcription factor IIS cooperates with the E3 ligase UBR5 to ubiquitinate the CDK9 subunit of the positive transcription elongation factor B.Coordinated activation of the origin licensing factor CDC6 and CDK2 in resting human fibroblasts expressing SV40 small T antigen and cyclin E.Targeting of CDK9 with indirubin 3'-monoxime safely and durably reduces HIV viremia in chronically infected humanized mice.UV Induces p21 rapid turnover independently of ubiquitin and Skp2.Human immunodeficiency virus type 1 infection induces cyclin T1 expression in macrophages.Ensemble-based modeling and rigidity decomposition of allosteric interaction networks and communication pathways in cyclin-dependent kinases: Differentiating kinase clients of the Hsp90-Cdc37 chaperone.SAR study on N2,N4-disubstituted pyrimidine-2,4-diamines as effective CDK2/CDK9 inhibitors and antiproliferative agents.MicroRNA-613 inhibits the progression of gastric cancer by targeting CDK9.MicroRNA-874 inhibits cell proliferation and invasion by targeting cyclin-dependent kinase 9 in osteosarcoma.DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery The CDK9-cyclin T1 complex mediates saturated fatty acid-induced vascular calcification by inducing expression of the transcription factor CHOP

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P2860

CDK9 is constitutively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2.

http://www.wikidata.org/entity/Q35161639

description

2003 nî lūn-bûn

@nan

2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2003年の論文

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2003年論文

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2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

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2003年論文

@zh-tw

2003年论文

@wuu

name

CDK9 is constitutively express ...... ession is independent of SKP2.

@ast

CDK9 is constitutively express ...... ession is independent of SKP2.

@en

type

label

CDK9 is constitutively express ...... ession is independent of SKP2.

@ast

CDK9 is constitutively express ...... ession is independent of SKP2.

@en

prefLabel

CDK9 is constitutively express ...... ession is independent of SKP2.

@ast

CDK9 is constitutively express ...... ession is independent of SKP2.

@en

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MCB.23.15.5165-5173.2003

P1433

Molecular and Cellular Biology

P1476

CDK9 is constitutively express ...... ession is independent of SKP2.

@en

P2093

Dale S Haines

http://www.w3.org/2001/XMLSchema#string

Joaquim Calbó

http://www.w3.org/2001/XMLSchema#string

Judit Garriga

http://www.w3.org/2001/XMLSchema#string

May Truongcao

http://www.w3.org/2001/XMLSchema#string

Renée M Marshall

http://www.w3.org/2001/XMLSchema#string

Sabyasachi Bhattacharya

http://www.w3.org/2001/XMLSchema#string

Xavier Graña

http://www.w3.org/2001/XMLSchema#string

P2860

PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro

Identification of multiple cyclin subunits of human P-TEFb

PISSLRE, a human novel CDC2-related protein kinase

Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome

A system for stable expression of short interfering RNAs in mammalian cells

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

Androgen receptor interacts with the positive elongation factor P-TEFb and enhances the efficiency of transcriptional elongation

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5165-5173

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scholarly article

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10.1128/MCB.23.15.5165-5173.2003

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15

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23

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2003-08-01T00:00:00Z

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10661478

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12861003

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P932

165719

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