Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs.
about
Gene-wide characterization of common quantitative trait loci for ABCB1 mRNA expression in normal liver tissues in the Chinese populationATP-binding cassette B1 gene polymorphisms, mRNA expression and chemosensitivity to paclitaxel in non-small cell lung cancer cells.ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell linesThe use of pharmacokinetic and pharmacodynamic data in the assessment of drug safety in early drug developmentA Study of Human Killer Cell Immunoglobulin-Like Receptor and Multidrug Resistance Gene Polymorphisms in Children With Immune Thrombocytopenia.Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?Combination analysis of NOS3, ABCB1 and IL23R polymorphisms with alcohol-induced osteonecrosis of the femoral head risk in Chinese malesClinical significance of ABCB1 genotyping in oncology.ABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer.The pharmacogenetics of imanitib.Donor P-gp polymorphisms strongly influence renal function and graft loss in a cohort of renal transplant recipients on cyclosporine therapy in a long-term follow-up.ABCB1 variation and treatment response in AIDS patients: initial results of the Henan cohortRaltegravir does not revert efflux activity of MDR1-P-glycoprotein in human MDR cells.Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene.Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia.From pharmacogenetics to personalized medicine: a vital need for educating health professionals and the community.Dexamethasone as a probe for vinorelbine clearance.Lack of sex-related differences in saquinavir pharmacokinetics in an HIV-seronegative cohort.Therapeutic implications of the MDR-1 gene.Influence of the CYP3A5 and MDR1 genetic polymorphisms on the pharmacokinetics of tacrolimus in healthy Korean subjects.Modulation of p-glycoprotein transport function at the blood-brain barrier.Mechanistic basis of adverse drug reactions: the perils of inappropriate dose schedules.CYP3A5 and ABCB1 genotype influence tacrolimus and sirolimus pharmacokinetics in renal transplant recipients.Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCG2: therapeutic implications.VEGF T-1498C polymorphism, a predictive marker of differentiation of colorectal adenocarcinomas in JapaneseABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.Genetics of inflammatory bowel disease: current status and future directions.Pharmacokinetic profiles of significant adverse events with crizotinib in Japanese patients with ABCB1 polymorphismCharacterization of the human MDR1 gene.Perioperative genomic profiles using structure-specific oligonucleotide probes.Impact of ATP-binding cassette, subfamily B, member 1 pharmacogenetics on tacrolimus-associated nephrotoxicity and dosage requirements in paediatric patients with liver transplant.ADHD pharmacogenetics across the life cycle: New findings and perspectives.Interethnic differences in pharmacokinetics of antibacterials.Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.YC-1, a novel potential anticancer agent, inhibit multidrug-resistant protein via cGMP-dependent pathway.Haloperidol is an inhibitor but not substrate for MDR1/P-glycoprotein.Association of polymorphisms in NR1I2 and ABCB1 genes with epilepsy treatment responses.Genome-wide single-nucleotide polymorphism map for Candida albicans.Population pharmacokinetics of cyclosporine in hematopoietic stem cell transplant patients: consideration of genetic polymorphisms.
P2860
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P2860
Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Pharmacogenetics of MDR1 and i ...... and pharmacodynamics of drugs.
@ast
Pharmacogenetics of MDR1 and i ...... and pharmacodynamics of drugs.
@en
type
label
Pharmacogenetics of MDR1 and i ...... and pharmacodynamics of drugs.
@ast
Pharmacogenetics of MDR1 and i ...... and pharmacodynamics of drugs.
@en
prefLabel
Pharmacogenetics of MDR1 and i ...... and pharmacodynamics of drugs.
@ast
Pharmacogenetics of MDR1 and i ...... and pharmacodynamics of drugs.
@en
P2093
P2860
P1433
P1476
Pharmacogenetics of MDR1 and i ...... and pharmacodynamics of drugs.
@en
P2093
Katsuhiko Okumura
Toshiyuki Sakaeda
Tsutomu Nakamura
P2860
P304
P356
10.1517/PHGS.4.4.397.22747
P577
2003-07-01T00:00:00Z