Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer's disease model.
about
G Protein-Coupled Receptors (GPCRs) in Alzheimer's Disease: A Focus on BACE1 Related GPCRsThe Different Therapeutic Choices with ARBs. Which One to Give? When? Why?Investigating Human Neurovascular Coupling Using Functional Neuroimaging: A Critical Review of Dynamic ModelsVasculoprotection as a Convergent, Multi-Targeted Mechanism of Anti-AD Therapeutics and InterventionsRelationship Between Antihypertensive Medications and Cognitive Impairment: Part II. Review of Physiology and Animal StudiesAdministration of bovine casein-derived peptide prevents cognitive decline in Alzheimer disease model mice.Effects of vascular risk factors, statins, and antihypertensive drugs on PiB deposition in cognitively normal subjects.Angiotensin-converting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-β and tau pathologyShould losartan be administered following brain injury?Neurovascular and Cognitive failure in Alzheimer's Disease: Benefits of Cardiovascular Therapy.Evidence to Consider Angiotensin II Receptor Blockers for the Treatment of Early Alzheimer's Disease.Neurovascular unit alteration in somatosensory cortex and enhancement of thermal nociception induced by amphetamine involves central AT1 receptor activation.Binaural blood flow control by astrocytes: listening to synapses and the vasculature.Crosstalk between angiotensin and the nonamyloidogenic pathway of Alzheimer's amyloid precursor protein.Losartan improves cerebrovascular function in a mouse model of Alzheimer's disease with combined overproduction of amyloid-β and transforming growth factor-β1.The brain renin-angiotensin system plays a crucial role in regulating body weight in diet-induced obesity in rats.Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure.Angiotensin-(1-7) is Reduced and Inversely Correlates with Tau Hyperphosphorylation in Animal Models of Alzheimer's Disease.Angiotensin II Causes Neuronal Damage in Stretch-Injured Neurons: Protective Effects of Losartan, an Angiotensin T1 Receptor Blocker.Macrophages come to mind as keys to cognitive decline.Imaging blood-brain barrier dysfunction as a biomarker for epileptogenesis.Losartan reduces the immediate and sustained increases in muscle sympathetic nerve activity after hyperacute intermittent hypoxia.Remodeling the susceptibility to stress-induced depression.Review: Neuropathology and behavioural features of transgenic murine models of Alzheimer's disease.Enalapril Alone or Co-Administered with Losartan Rescues Cerebrovascular Dysfunction, but not Mnemonic Deficits or Amyloidosis in a Mouse Model of Alzheimer's Disease.Within the Brain: The Renin Angiotensin System.Implications of PI3K/AKT/PTEN Signaling on Superoxide Dismutases Expression and in the Pathogenesis of Alzheimer's Disease.Targeting Renin-Angiotensin System Against Alzheimer's Disease.Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice.Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer's disease using functional laser speckle contrast imaging.Angiotensin II type 1 receptor blocker losartan attenuates locomotor, anxiety-like behavior, and passive avoidance learning deficits in a sub-chronic stress model
P2860
Q26752403-A66F226D-4A35-4FC1-874A-959D8241E231Q26768696-029E2F60-1544-40C1-8989-708659596C6AQ26770783-3555716A-4446-428A-8824-E1893E927ECBQ26781557-2D1D0951-DAF6-4558-BBA5-1625BD2ECA89Q28074637-3C90D0EE-922B-4F64-AD9E-874829142145Q36270062-0593A4D3-C422-43BB-A849-EA24D820C05EQ36933792-C86984E2-E73D-4724-B556-92A2710A9380Q37440125-5F9AB62B-0F8F-4360-806E-36A11E7E56DDQ38262865-3F757EF5-E46B-4AA1-8C1D-EA660AE00036Q38781022-2D751ED1-D00C-46A7-BF52-FD534BEA35A0Q38781028-801DFD60-6468-4936-A0F1-F9B765F8A13DQ38816549-1A4DC97B-2A6A-451A-9D85-A4A7143CA81EQ38952233-E276CBC5-7D52-4C97-A92D-15C4569A4F96Q39012575-3C84A054-19E8-4A9F-B58E-3D1C0834CACAQ39623328-A8FA35B3-4731-4B48-B435-9920B6381C17Q40559527-974B763E-D760-4EEA-BF91-2CF4D86330CFQ41165985-B96CDCD4-ABA8-4EAA-BF52-FA8D381C5434Q46152975-86D185BB-E192-4287-BCAB-7E3597F53DB3Q46265113-5FFB4391-2DD0-4232-834E-648423B38024Q46423522-9626EE35-ECB4-4FFB-9706-C3B0F3138CB0Q46663613-69223A17-8DBE-4AA3-8BBA-74E55E97B88EQ47775279-C1D54C6C-FAC7-4487-8870-A0F9C9436611Q48073057-9531B249-E192-47CA-AB52-F74B3FE1905EQ48113034-9E7F7B58-DC11-43F8-87D4-73AA46446171Q48873920-0F157CC7-3A07-4491-AABC-59CECDF31EEEQ51762826-2628D51A-C325-4364-94D7-EC9654D66B08Q52574481-B69B2E08-DB11-463E-8D03-A31077C4FF9BQ55007046-FD567C28-2D48-4DE3-93B7-B74A659813A1Q55028803-48072BB1-38EF-461D-9AFD-9D95C2EDA144Q55054299-BB57BA29-8F6E-465A-9F47-19CDE1672AA7Q58805051-2E653C73-0AAC-47EE-97C4-B9F000FC6BE7
P2860
Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer's disease model.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Angiotensin II type 1 receptor ...... an Alzheimer's disease model.
@ast
Angiotensin II type 1 receptor ...... an Alzheimer's disease model.
@en
type
label
Angiotensin II type 1 receptor ...... an Alzheimer's disease model.
@ast
Angiotensin II type 1 receptor ...... an Alzheimer's disease model.
@en
prefLabel
Angiotensin II type 1 receptor ...... an Alzheimer's disease model.
@ast
Angiotensin II type 1 receptor ...... an Alzheimer's disease model.
@en
P2093
P1476
Angiotensin II type 1 receptor ...... an Alzheimer's disease model.
@en
P2093
Brice Ongali
Clotilde Lecrux
Edith Hamel
Hans Imboden
Nektaria Nicolakakis
Panayiota Papadopoulos
Tahar Aboulkassim
Xin-Kang Tong
P304
P356
10.1016/J.NBD.2014.04.018
P577
2014-05-05T00:00:00Z