Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells.
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Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnoverActin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary glandCell type-specific activation of AKT and ERK signaling pathways by small negatively-charged magnetic nanoparticlesApproaches and tools for modeling signaling pathways and calcium dynamics in neuronsProlactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer CellsEssential role of endogenous prolactin and CDK7 in estrogen-induced upregulation of the prolactin receptor in breast cancer cellsImpact of subdomain D1 of the short form S1b of the human prolactin receptor on its inhibitory action on the function of the long form of the receptor induced by prolactin.Gastrointestinal hormones/neurotransmitters and growth factors can activate P21 activated kinase 2 in pancreatic acinar cells by novel mechanismsCXCL12 induces connective tissue growth factor expression in human lung fibroblasts through the Rac1/ERK, JNK, and AP-1 pathways.Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise.Prolactin induces up-regulation of its cognate receptor in breast cancer cells via transcriptional activation of its generic promoter by cross-talk between ERα and STAT5Bioactive prolactin levels and risk of breast cancer: a nested case-control study.Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells.Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven LeukemogenesisA Residue Quartet in the Extracellular Domain of the Prolactin Receptor Selectively Controls Mitogen-activated Protein Kinase SignalingSrc tyrosyl phosphorylates cortactin in response to prolactin.Tyrosyl phosphorylated serine-threonine kinase PAK1 is a novel regulator of prolactin-dependent breast cancer cell motility and invasion.Prolactin gene expression in primary central nervous system tumors.AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion.A 20-year prospective study of plasma prolactin as a risk marker of breast cancer development.Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis.Role of EGF/ERBB1 in the transcriptional regulation of the prolactin receptor independent of estrogen and prolactin in breast cancer cells.Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3Kα-selective Inhibitors in Breast Cancer.Hypothesis: prolactin is tumorigenic to human breast: dispelling the myth that prolactin-induced mammary tumors are rodent-specific.Triennial Lactation Symposium: Prolactin: The multifaceted potentiator of mammary growth and function.PAK signaling in cancer.Remarkable reductions of PAKs in the brain tissues of scrapie-infected rodent possibly linked closely with neuron loss.Prolactin Receptor-Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity.Histone H1 and Chromosomal Protein HMGN2 Regulate Prolactin-induced STAT5 Transcription Factor Recruitment and Function in Breast Cancer Cells.The nuclear translocation of ERK1/2 as an anticancer target.Identification of NEK3 Kinase Threonine 165 as a Novel Regulatory Phosphorylation Site That Modulates Focal Adhesion Remodeling Necessary for Breast Cancer Cell Migration.PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling.Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas.Fluorescence resonance energy transfer based quantitative analysis of feedforward and feedback loops in epidermal growth factor receptor signaling and the sensitivity to molecular targeting drugs.Predicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approach.Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols.Endothelial Cdc42 deficiency impairs endothelial regeneration and vascular repair after inflammatory vascular injury.Stromal-epithelial interactions modulate cross-talk between prolactin receptor and HER2/Neu in breast cancer.Neuregulin 1 up-regulates the expression of nicotinic acetylcholine receptors through the ErbB2/ErbB3-PI3K-MAPK signaling cascade in adult autonomic ganglion neurons.
P2860
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P2860
Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Prolactin-stimulated activatio ...... athway in breast cancer cells.
@ast
Prolactin-stimulated activatio ...... athway in breast cancer cells.
@en
type
label
Prolactin-stimulated activatio ...... athway in breast cancer cells.
@ast
Prolactin-stimulated activatio ...... athway in breast cancer cells.
@en
prefLabel
Prolactin-stimulated activatio ...... athway in breast cancer cells.
@ast
Prolactin-stimulated activatio ...... athway in breast cancer cells.
@en
P2860
P50
P1433
P1476
Prolactin-stimulated activatio ...... athway in breast cancer cells.
@en
P2093
Sirisha Achanta
P2860
P304
P356
10.1016/J.CELLSIG.2011.06.014
P577
2011-06-25T00:00:00Z