Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone - Wikidata - wikimedia - TriplyDB

Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone

Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone

http://www.wikidata.org/entity/Q35166074

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Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity Microscale insights into pneumococcal antibiotic mutant selection windows Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection Is in vitro antibiotic combination more effective than single-drug therapy against anthrax?Doxycycline reduces mortality and injury to the brain and cochlea in experimental pneumococcal meningitis.Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury Beneficial and Harmful Interactions of Antibiotics with Microbial Pathogens and the Host Innate Immune System Role of pore-forming toxins in bacterial infectious diseases.Docosahexaenoic acid and eicosapentaenoic acid antagonize the proinflammatory interactions of pneumolysin with human neutrophils Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue.Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity.The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model Differences in clinical manifestation of Streptococcus pneumoniae infection are not correlated with in vitro production and release of the virulence factors pneumolysin and lipoteichoic and teichoic acids.Persistence of pneumolysin in the cerebrospinal fluid of patients with pneumococcal meningitis is associated with mortality Rifampin use in acute community-acquired meningitis in intensive care units: the French retrospective cohort ACAM-ICU study.Anti-inflammatory activity of ansamycins.Pathogen- and host-directed anti-inflammatory activities of macrolide antibiotics Treatment and prevention strategies to combat pediatric pneumococcal meningitis.Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest Systemic expression of cytokine production in patients with severe pneumococcal pneumonia: effects of treatment with a beta-lactam versus a fluoroquinolone.Controversies in the treatment of pneumococcal community-acquired pneumonia.Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium.Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes.Bacterial meningitis: new therapeutic approaches.Antivirulence activity of azithromycin in Pseudomonas aeruginosa Bacterial meningitis: an update of new treatment options.Disentangling competence for genetic transformation and virulence in Streptococcus pneumoniae.Strategies to increase the activity of microglia as efficient protectors of the brain against infections.Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation.Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis.Streptococcus pneumoniae-induced inhibition of rat ependymal cilia is attenuated by antipneumolysin antibody.Pneumolysin activates neutrophil extracellular trap formation.Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice.Apoptosis of hippocampal neurons in organotypic slice culture models: direct effect of bacteria revisited.Paul Ehrlich, a prescient pioneer in the field of antimicrobial chemotherapy: what did he foresee a century ago?Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid.Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema.

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P2860

Reduced release of pneumolysin by Streptococcus pneumoniae in vitro and in vivo after treatment with nonbacteriolytic antibiotics in comparison to ceftriaxone

http://www.wikidata.org/entity/Q35166074

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2003 nî lūn-bûn

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2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2003 թվականի օգոստոսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Reduced release of pneumolysin ...... s in comparison to ceftriaxone

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Reduced release of pneumolysin ...... s in comparison to ceftriaxone

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Reduced release of pneumolysin ...... s in comparison to ceftriaxone

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Reduced release of pneumolysin ...... s in comparison to ceftriaxone

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AAC.47.8.2649-2654.2003

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Antimicrobial Agents and Chemotherapy

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Reduced release of pneumolysin ...... s in comparison to ceftriaxone

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P2093

Alexander Siemer

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Annette Spreer

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Gregor Zysk

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Helmut Eiffert

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Holger Kerstan

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Joachim Gerber

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Roland Nau

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Tobias Böttcher

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P2860

Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis

Proinflammatory interactions of pneumolysin with human neutrophils.

Detection of pneumolysin in sputum.

The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin

Pneumococcal virulence factors: structure and function

Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase.

Neuronal injury in bacterial meningitis: mechanisms and implications for therapy.

Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae

Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.

Bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in cerebrospinal fluid of children with acute bacterial meningitis.

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2649-2654

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scholarly article

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10.1128/AAC.47.8.2649-2654.2003

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8

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Timothy J Mitchell

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2003-08-01T00:00:00Z

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12878534

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166091

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