Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase
about
A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutasePotential Role of Selenoenzymes and Antioxidant Metabolism in relation to Autism Etiology and PathologyStructures of the N-terminal modules imply large domain motions during catalysis by methionine synthaseA disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactorInsights into the reactivation of cobalamin-dependent methionine synthaseVisualizing molecular juggling within a B12-dependent methyltransferase complexCatalysis of methyl group transfers involving tetrahydrofolate and B(12)Ethanol lowers glutathione in rat liver and brain and inhibits methionine synthase in a cobalamin-dependent mannerInsight into the mechanism of biological methanol activation based on the crystal structure of the methanol-cobalamin methyltransferase complex.Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autismMacromolecular juggling by ubiquitylation enzymes.Spectroscopic study of the cobalamin-dependent methionine synthase in the activation conformation: effects of the Y1139 residue and S-adenosylmethionine on the B12 cofactor.Cobalamin- and corrinoid-dependent enzymesStructural insights into methyltransfer reactions of a corrinoid iron-sulfur protein involved in acetyl-CoA synthesis.Structural basis for gene regulation by a B12-dependent photoreceptor.Alternatively Spliced Methionine Synthase in SH-SY5Y Neuroblastoma Cells: Cobalamin and GSH Dependence and Inhibitory Effects of Neurotoxic Metals and Thimerosal.Ligand trans influence governs conformation in cobalamin-dependent methionine synthaseBiography of Martha L. LudwigA love affair with vitamins.Large-scale domain motions and pyridoxal-5'-phosphate assisted radical catalysis in coenzyme B12-dependent aminomutases.Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.A B12-dependent radical SAM enzyme involved in oxetanocin A biosynthesis.Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.Intraprotein transmethylation via a CH3-Co(iii) species in myoglobin reconstituted with a cobalt corrinoid complex.
P2860
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P2860
Factors modulating conformational equilibria in large modular proteins: a case study with cobalamin-dependent methionine synthase
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Factors modulating conformatio ...... -dependent methionine synthase
@ast
Factors modulating conformatio ...... -dependent methionine synthase
@en
type
label
Factors modulating conformatio ...... -dependent methionine synthase
@ast
Factors modulating conformatio ...... -dependent methionine synthase
@en
prefLabel
Factors modulating conformatio ...... -dependent methionine synthase
@ast
Factors modulating conformatio ...... -dependent methionine synthase
@en
P2093
P2860
P356
P1476
Factors modulating conformatio ...... -dependent methionine synthase
@en
P2093
Martha L Ludwig
Rowena G Matthews
Vahe Bandarian
P2860
P304
P356
10.1073/PNAS.1133218100
P407
P577
2003-06-27T00:00:00Z