Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease
about
Clinical immunologic approaches for the treatment of Alzheimer's diseaseNasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer diseaseImmunization with the SDPM1 peptide lowers amyloid plaque burden and improves cognitive function in the APPswePSEN1(A246E) transgenic mouse model of Alzheimer's disease.Immunotherapy in Parkinson's Disease: Micromanaging Alpha-Synuclein AggregationInteraction between therapeutic interventions for Alzheimer's disease and physiological Aβ clearance mechanismsCD4 T cells in immunity and immunotherapy of Alzheimer's diseaseReduced β-amyloid pathology in an APP transgenic mouse model of Alzheimer's disease lacking functional B and T cellsNeuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's diseaseAbeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease.Aging enhances release of exosomal cytokine mRNAs by Aβ1-42-stimulated macrophages.Norovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer's disease.Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.T cells specifically targeted to amyloid plaques enhance plaque clearance in a mouse model of Alzheimer's diseaseDNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice.Can peripheral leukocytes be used as Alzheimer's disease biomarkers?Targeting the endocannabinoid system in Alzheimer's disease.Amyloid-beta immunotherapy for Alzheimer's diseaseMaintenance of immune tolerance to a neo-self acetylcholine receptor antigen with aging: implications for late-onset autoimmunityDNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs.A new DNA vaccine fused with the C3d-p28 induces a Th2 immune response against amyloid-betaBeta-amyloid peptides enhance the proliferative response of activated CD4CD28 lymphocytes from Alzheimer disease patients and from healthy elderly.CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.Nonviral Abeta DNA vaccine therapy against Alzheimer's disease: long-term effects and safetyAlzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet.Abeta DNA vaccination for Alzheimer's disease: focus on disease prevention.The immunological potency and therapeutic potential of a prototype dual vaccine against influenza and Alzheimer's disease.Vaccine-induced Aβ-specific CD8+ T cells do not trigger autoimmune neuroinflammation in a murine model of Alzheimer's disease.Autoreactive-Aβ antibodies promote APP β-secretase processing.DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice.Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhageVGF expression by T lymphocytes in patients with Alzheimer's diseaseInteraction of astrocytes and T cells in physiological and pathological conditionsThe immune system, amyloid-beta peptide, and Alzheimer's disease.Immune shaping and the development of Alzheimer's disease vaccines.Current concepts in therapeutic strategies targeting cognitive decline and disease modification in Alzheimer's disease.Yeast expressed foldable quadrivalent Aβ15 elicited strong immune response against Aβ without Aβ-specific T cell response in wild C57BL/6 mice.The PPAR-gamma Agonist 15-Deoxy-Delta-Prostaglandin J(2) Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease.Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.
P2860
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P2860
Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Increased T cell reactivity to ...... atients with Alzheimer disease
@ast
Increased T cell reactivity to ...... atients with Alzheimer disease
@en
type
label
Increased T cell reactivity to ...... atients with Alzheimer disease
@ast
Increased T cell reactivity to ...... atients with Alzheimer disease
@en
prefLabel
Increased T cell reactivity to ...... atients with Alzheimer disease
@ast
Increased T cell reactivity to ...... atients with Alzheimer disease
@en
P2093
P2860
P356
P1476
Increased T cell reactivity to ...... atients with Alzheimer disease
@en
P2093
Alon Monsonego
Amit Bar-Or
Andrew E Budson
Arnon Karni
Dennis J Selkoe
Jeffery I Krieger
Victor Zota
P2860
P304
P356
10.1172/JCI200318104
P407
P577
2003-08-01T00:00:00Z