A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.

A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.

Item
http://www.wikidata.org/entity/Q35170886
A conserved phosphatase destroys toxic glycolytic side products in mammals and yeast.Saccharomyces cerevisiae Forms D-2-Hydroxyglutarate and Couples Its Degradation to D-Lactate Formation via a Cytosolic Transhydrogenase.Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive StressHypoxia Induces Production of L-2-Hydroxyglutarate.Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation.L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration.L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pHAcidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling.Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth.Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates.Increased glutarate production by blocking the glutaryl-CoA dehydrogenation pathway and a catabolic pathway involving L-2-hydroxyglutarate.Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory
P2860

A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.

Item
http://www.wikidata.org/entity/Q35170886
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
@ast
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
@en
type
label
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
@ast
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
@en
prefLabel
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
@ast
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0119540
P407
P433
P478
P50
P577
P5875
P698
P932