Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis. - Wikidata - wikimedia - TriplyDB

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.

http://www.wikidata.org/entity/Q35170957

about

Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH)Building a better bacillus: the emergence of Mycobacterium tuberculosis Synthetic biology to access and expand nature's chemical diversity Aminobenzoates as building blocks for natural product assembly lines.Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis Strain prioritization for natural product discovery by a high-throughput real-time PCR method.Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners.Identification and analysis of the paulomycin biosynthetic gene cluster and titer improvement of the paulomycins in Streptomyces paulus NRRL 8115 Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029.Structure of the ent-Copalyl Diphosphate Synthase PtmT2 from Streptomyces platensis CB00739, a Bacterial Type II Diterpene Synthase.A Mutasynthetic Library of Platensimycin and Platencin Analogues.Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.Biosynthetic Origin of the Ether Ring in Platensimycin.Discovery and Characterization of a New Family of Diterpene Cyclases in Bacteria and Fungi.A Facile Semi-Synthetic Approach towards Halogen-Substituted Aminobenzoic Acid Analogues of Platensimycin.Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining Functional conservation of the capacity for ent-kaurene biosynthesis and an associated operon in certain rhizobia.Biosynthetic potential-based strain prioritization for natural product discovery: a showcase for diterpenoid-producing actinomycetes.Diterpene synthases and their responsible cyclic natural products.Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis.Nutritional control of antibiotic production by Streptomyces platensis MA7327: importance of l-aspartic acid.A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase.Isolation and structural elucidation of glucoside congeners of platencin from Streptomyces platensis SB12600.Bacterial terpene cyclases.Target-specific identification and characterization of the putative gene cluster for brasilinolide biosynthesis revealing the mechanistic insights and combinatorial synthetic utility of 2-deoxy-l-fucose biosynthetic enzymes.Structural and Chemical Biology of Terpenoid Cyclases.Extending a Single Residue Switch for Abbreviating Catalysis in Plant ent-Kaurene Synthases.Characterization of an orphan diterpenoid biosynthetic operon from Salinispora arenicola.Identification of Chimeric αβγ Diterpene Synthases Possessing both Type II Terpene Cyclase and Prenyltransferase Activities.Actinomycetes: still a source of novel antibiotics.Genetic engineering of Streptomyces bingchenggensis to produce milbemycins A3/A4 as main components and eliminate the biosynthesis of nanchangmycin.A nitrous acid biosynthetic pathway for diazo group formation in bacteria.Identification of a new diterpene biosynthetic gene cluster that produces O-methylkolavelool in Herpetosiphon aurantiacus.Aurachin SS, a new antibiotic from Streptomyces sp. NA04227.Biosynthesis of thiocarboxylic acid-containing natural products.A second RNA-binding protein is essential for ethanol tolerance provided by the bacterial OLE ribonucleoprotein complex Natural separation of the acyl-CoA ligase reaction results in a non-adenylating enzyme

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P2860

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.

http://www.wikidata.org/entity/Q35170957

description

2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Dedicated ent-kaurene and ent- ...... in and platencin biosynthesis.

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Dedicated ent-kaurene and ent- ...... in and platencin biosynthesis.

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Dedicated ent-kaurene and ent- ...... in and platencin biosynthesis.

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Dedicated ent-kaurene and ent- ...... in and platencin biosynthesis.

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Dedicated ent-kaurene and ent- ...... in and platencin biosynthesis.

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PNAS.1106919108

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Proceedings of the National Academy of Sciences of the United States of America

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Dedicated ent-kaurene and ent- ...... cin and platencin biosynthesis

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Ben Shen

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Evelyn Wendt-Pienkowski

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Jeffrey Casper

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Michael J Smanski

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Scott R Rajski

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Shuangjun Lin

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Yihua Chen

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Zhiguo Yu

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P2860

Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes

Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes

Plant terpenoid synthases: molecular biology and phylogenetic analysis

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates ,

Diterpene cyclases and the nature of the isoprene fold

Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America

The challenge of emerging and re-emerging infectious diseases

A structural model of the membrane-bound aromatic prenyltransferase UbiA from E. coli.

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin.

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10.1073/PNAS.1106919108

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33

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108

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Ryan M Peterson

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51555557

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