A mechanistic perspective on the chemistry of DNA repair glycosylases.
about
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNAThymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sitesRepair of cyclobutane pyrimidine dimers or dimethylsulfate damage in DNA is identical in normal or telomerase-immortalized human skin fibroblasts.DNA bending by M.EcoKI methyltransferase is coupled to nucleotide flipping.Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexesKinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylaseMechanism and function of oxidative reversal of DNA and RNA methylationSolution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase IDNA damage recognition and repair by 3-methyladenine DNA glycosylase I (TAG)Enzymatic capture of an extrahelical thymine in the search for uracil in DNAA New Protein Architecture for Processing Alkylation Damaged DNA: The Crystal Structure of DNA Glycosylase AlkDCrystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognitionAn unprecedented nucleic acid capture mechanism for excision of DNA damageAnalysis of substrate specificity of Schizosaccharomyces pombe Mag1 alkylpurine DNA glycosylaseSculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine-thymine mismatchCrystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNACrystal structure of family 4 uracil-DNA glycosylase from Sulfolobus tokodaii and a function of tyrosine 170 in DNA bindingDependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairsSpecificity and catalytic mechanism in family 5 uracil DNA glycosylaseCorrelated Mutation in the Evolution of Catalysis in Uracil DNA Glycosylase SuperfamilyBiorecognition by DNA oligonucleotides after exposure to photoresists and resist removers.Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeatsNontarget DNA binding shapes the dynamic landscape for enzymatic recognition of DNA damage.Dynamic opening of DNA during the enzymatic search for a damaged base.Alkylpurine glycosylase D employs DNA sculpting as a strategy to extrude and excise damaged basesMimicking damaged DNA with a small molecule inhibitor of human UNG2.Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase.The substrate binding interface of alkylpurine DNA glycosylase AlkDThe mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanineIrreversible inhibition of DNA polymerase β by small-molecule mimics of a DNA lesionExcision of a lyase-resistant oxidized abasic lesion from DNA.Solid state 2H NMR analysis of furanose ring dynamics in DNA containing uracilHuman base excision repair creates a bias toward -1 frameshift mutationsDNA repair deficiency in neurodegeneration.Recent advances in the structural mechanisms of DNA glycosylasesInterplay between base excision repair activity and toxicity of 3-methyladenine DNA glycosylases in an E. coli complementation systemOn the molecular basis of uracil recognition in DNA: comparative study of T-A versus U-A structure, dynamics and open base pair kinetics.The effect of a G:T mispair on the dynamics of DNAChemical mapping of cytosines enzymatically flipped out of the DNA helix.
P2860
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P2860
A mechanistic perspective on the chemistry of DNA repair glycosylases.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A mechanistic perspective on the chemistry of DNA repair glycosylases.
@ast
A mechanistic perspective on the chemistry of DNA repair glycosylases.
@en
type
label
A mechanistic perspective on the chemistry of DNA repair glycosylases.
@ast
A mechanistic perspective on the chemistry of DNA repair glycosylases.
@en
prefLabel
A mechanistic perspective on the chemistry of DNA repair glycosylases.
@ast
A mechanistic perspective on the chemistry of DNA repair glycosylases.
@en
P356
P1433
P1476
A mechanistic perspective on the chemistry of DNA repair glycosylases.
@en
P2093
James T Stivers
Yu Lin Jiang
P304
P356
10.1021/CR010219B
P577
2003-07-01T00:00:00Z