Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells. - Wikidata - wikimedia - TriplyDB

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells.

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells.

http://www.wikidata.org/entity/Q35176105

about

Glucose transport: meeting the metabolic demands of cancer, and applications in glioblastoma treatment WZB117 (2-Fluoro-6-(m-hydroxybenzoyloxy) Phenyl m-Hydroxybenzoate) Inhibits GLUT1-mediated Sugar Transport by Binding Reversibly at the Exofacial Sugar Binding Site.Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression.Phenotypic and microRNA transcriptomic profiling of the MDA-MB-231 spheroid-enriched CSCs with comparison of MCF-7 microRNA profiling dataset.Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells.Cancer Stem Cells in Small Cell Lung Cancer Cell Line H446: Higher Dependency on Oxidative Phosphorylation and Mitochondrial Substrate-Level Phosphorylation than Non-Stem Cancer Cells miRNA-regulated delivery of lincRNA-p21 suppresses β-catenin signaling and tumorigenicity of colorectal cancer stem cells Monitoring cancer stem cells: insights into clinical oncology.Inhibiting Notch Activity in Breast Cancer Stem Cells by Glucose Functionalized Nanoparticles Carrying γ-secretase Inhibitors Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.Ras-related associated with diabetes gene acts as a suppressor and inhibits Warburg effect in hepatocellular carcinoma.The neuropilin-1 receptor mediates enhanced tumor delivery of H2K polyplexes.The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo.Hypoxia-induced angiotensin II by the lactate-chymase-dependent mechanism mediates radioresistance of hypoxic tumor cells.Metabolic enzymes: key modulators of functionality in cancer stem-like cells.Cancer stem cells: a potential target for cancer therapy.2-Methoxyestradiol enhances radiosensitivity in radioresistant melanoma MDA-MB-435R cells by regulating glycolysis via HIF-1α/PDK1 axis.The role of octamer binding transcription factors in glioblastoma multiforme.Cancer stem cell molecular reprogramming of the Warburg effect in glioblastomas: a new target gleaned from an old concept.Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation.Bioinformatic Profiling Identifies a Glucose-Related Risk Signature for the Malignancy of Glioma and the Survival of Patients.The hypoxic microenvironment: A determinant of cancer stem cell evolution.PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells Role of glucose metabolism related gene GLUT1 in the occurrence and prognosis of colorectal cancer.Metabolic Plasticity of Stem Cells and Macrophages in Cancer.Antitumor activity of gemcitabine against high-grade meningioma in vitro and in vivo.Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug.Friend or foe? Mitochondria as a pharmacological target in cancer treatment.Validity and clinical impact of glucose transporter 1 expression in colorectal cancer.The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1α signaling.Brain Transport Profiles of Ginsenoside Rb1 by Glucose Transporter 1: In Vitro and in Vivo.Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma.Constraint based modeling of metabolism allows finding metabolic cancer hallmarks and identifying personalized therapeutic windows.Mitochondrial metabolism and cancer VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel Ultrasound microbubbles mediated miR-let-7b delivery into CD133 ovarian cancer stem cells

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P2860

Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells.

http://www.wikidata.org/entity/Q35176105

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Targeting the facilitative glu ...... capacity of cancer stem cells.

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Targeting the facilitative glu ...... capacity of cancer stem cells.

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type

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Targeting the facilitative glu ...... capacity of cancer stem cells.

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Targeting the facilitative glu ...... capacity of cancer stem cells.

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prefLabel

Targeting the facilitative glu ...... capacity of cancer stem cells.

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Targeting the facilitative glu ...... capacity of cancer stem cells.

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ONCOTARGET.2892

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Targeting the facilitative glu ...... capacity of cancer stem cells.

@en

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Chifumi Kitanaka

http://www.w3.org/2001/XMLSchema#string

Hiroyuki Takeda

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Keita Shibuya

http://www.w3.org/2001/XMLSchema#string

Manabu Seino

http://www.w3.org/2001/XMLSchema#string

Masashi Okada

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Shizuka Seino

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Shuhei Suzuki

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P2860

Hallmarks of Cancer: The Next Generation

Targeting cellular metabolism to improve cancer therapeutics

Cancer cell metabolism: implications for therapeutic targets

Stem cells, cancer, and cancer stem cells

Glycolysis inhibition inactivates ABC transporters to restore drug sensitivity in malignant cells

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake.

Metabolic genes in cancer: their roles in tumor progression and clinical implications

Targeting the K-Ras--JNK axis eliminates cancer stem-like cells and prevents pancreatic tumor formation.

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine.

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651-661

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scholarly article

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10.18632/ONCOTARGET.2892

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2

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6

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25528771

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4359246

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