Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells. - Wikidata - wikimedia - TriplyDB

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

http://www.wikidata.org/entity/Q35180070

about

Cyclic AMP dynamics in the pancreatic β-cell An age-dependent interaction with leptin unmasks ghrelin's bone-protective effects Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts β-cell Function.Nutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cells The β-cell GHSR and downstream cAMP/TRPM2 signaling account for insulinostatic and glycemic effects of ghrelin A high-fat diet regulates gastrin and acid secretion through primary cilia.Pharmacological characterization of the first in class clinical candidate PF-05190457: a selective ghrelin receptor competitive antagonist with inverse agonism that increases vagal afferent firing and glucose-dependent insulin secretion ex vivo.Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.Role of SST, CORT and ghrelin and its receptors at the endocrine pancreas.Ghrelin signalling in β-cells regulates insulin secretion and blood glucose.Involvement of thermosensitive TRP channels in energy metabolism.Microfluidic perfusion systems for secretion fingerprint analysis of pancreatic islets: applications, challenges and opportunities.Ghrelin, CCK, GLP-1, and PYY(3-36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB.Potentiation of Glucose-stimulated Insulin Secretion by the GPR40-PLC-TRPC Pathway in Pancreatic β-Cells.Ghrelin and des-acyl ghrelin inhibit aromatase expression and activity in human adipose stromal cells: suppression of cAMP as a possible mechanism.Analgesic effect of the neuropeptide cortistatin in murine models of arthritic inflammatory pain.GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose.Ghrelin, ghrelin-O-acyl transferase, nucleobindin-2/nesfatin-1 and prohormone convertases in the pancreatic islets of Sprague Dawley rats during development.Subchronic olanzapine treatment decreases the expression of pancreatic glucose transporter 2 in rat pancreatic β cells.Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet β-cells.Inhibition of voltage-dependent potassium channels mediates cAMP-potentiated insulin secretion in rat pancreatic β cells.What Has Bariatric Surgery Taught Us About the Role of the Upper Gastrointestinal Tract in the Regulation of Postprandial Glucose Metabolism?

P2860

Q27008275-5840EE44-3C05-4605-A692-3C94D22DD1DB Q33569660-D92E234D-F4B3-4CBA-9EAD-04621C22757D Q33603660-A3A1DE8F-3B95-4C6B-97E3-C6DCDBB1F542 Q35392914-5091A315-E02C-4246-A299-8B7C6146D4E4 Q36060564-3DC37496-1EDE-4136-8AAF-B69C0A90F4F2 Q36117413-A26DBDFA-7DDB-4EDE-BAB5-187B1F523D55 Q36797357-F8C880C3-63AE-4832-9228-3BC9BF3C8998 Q37039704-911FF5F8-25FF-43D7-964C-221D9FC0101A Q38060718-1E90144E-DB9A-433A-A070-13FEE083F3A0 Q38247032-60ED378D-DD74-4ACF-8CEF-6134722489F5 Q38665813-C7ED7FE7-91D2-4F14-B3BA-0842659B397D Q38687419-8DA30820-0767-40AB-9515-91BFA6D81893 Q39047697-029CFD85-5A1B-45CE-AD45-9CC3F307AE4B Q41848207-B83220D4-B6A6-4BF4-9FB4-9A5490151AE8 Q42462821-0D1AF771-5E73-493B-9B2A-FA8849CA9A05 Q45366182-73010758-0A9E-443D-B1C0-4AFAE5170E75 Q49414493-113DF11A-1078-4752-A762-1C4CFCCD4B8C Q50520844-8D5B631C-BDAC-4368-A802-CCE23586463E Q51137100-43EA0F00-B04D-4EE5-8247-8A14F9DEF2E6 Q53159760-D28D9898-F721-46A3-82AD-CAE8B47C2E45 Q53565636-BC55E67A-AA33-4D46-B2AC-BB0A273911D6 Q55555487-0798CD28-1B86-42A7-A626-209A65C20584

P2860

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

http://www.wikidata.org/entity/Q35180070

description

2011 nî lūn-bûn

@nan

2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

@ast

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

@en

type

label

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

@ast

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

@en

prefLabel

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

@ast

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells.

@en

P1433

Q35180070-68EC93A0-CA4E-4031-8A06-041BE83723E6

P1476

Q35180070-1FEC4E19-2413-437B-9CC4-FDD1C800D068

P2093

Q35180070-1587715B-F61B-4AF6-97B2-F9BCF0C58601

Q35180070-4CD20B9D-2D77-4FEF-AB9D-8DC4817AF94D

Q35180070-6C2BFEF9-4607-4BBC-B5AA-D5D42F98332D

Q35180070-7CB8A5BA-6036-4705-B294-212874831EAB

Q35180070-7CFC5C0E-95BF-4524-8207-973DF4C046FD

Q35180070-82AFE1B6-0774-4E00-820D-3DC98BD36FBA

Q35180070-91D8BD84-F528-4989-A71B-F8433B3D0868

Q35180070-C089686C-8081-4CE4-A764-00054627D013

P2860

Q35180070-02C0C0E7-2E64-4F18-A05E-47EC6D0EE515

Q35180070-0A2601F0-AD48-4024-A068-99C663FBBA88

Q35180070-0C7C14CB-467B-4076-9FDD-8CD72951B04F

Q35180070-0EC535CA-7EFB-4BC4-BD8F-AE5947BDEC73

Q35180070-111BB860-7B1C-47C1-B5B2-A4B6C0E6CBE0

Q35180070-1CC09295-486A-4B0C-9817-BEF926D22F52

Q35180070-242A68BA-11A4-4308-8785-1763868C1A79

Q35180070-2BA412F3-6793-4D06-931F-4C8C5EC30279

Q35180070-3667CA6D-7EE5-43E6-B1DB-F6031E1F385E

Q35180070-38A32C00-67BA-4CC8-A53E-7FDAB6285790

P304

Q35180070-8E804F2C-9EDF-4387-9906-F5AA6DEB1634

P31

Q35180070-7219B848-F173-4379-BD03-579EE4E6A17B

P356

Q35180070-51CCBA73-D6C6-4DAC-BEF0-CE4D61AF2FF6

P407

Q35180070-0DB048A8-F1FF-46CB-8F64-2307D1CD864A

P433

Q35180070-9068FD40-C059-4CDC-BFA6-EDD838E05A42

P478

Q35180070-637EA881-04E8-48A5-BC6A-290945F694E5

P50

Q35180070-359C99E7-1AEC-41E4-B77C-28871E4697FB

Q35180070-6342DD7B-761A-4BAA-AC9D-B3B1106D73D7

P577

Q35180070-50C50198-12E6-4932-B2A4-3BD55998FEB7

P5875

Q35180070-93D260BB-635A-4634-9323-4692FC379F33

P698

Q35180070-D8D9E34E-53BF-415A-ACC5-8D7BAD0E2669

P932

Q35180070-986C740C-2984-46D5-84BA-7EDB0D935258

P356

P1433

P1476

Ghrelin attenuates cAMP-PKA signaling to evoke insulinostatic cascade in islet β-cells

@en

P2093

Anders Tengholm

http://www.w3.org/2001/XMLSchema#string

Boldbaatar Damdindorj

http://www.w3.org/2001/XMLSchema#string

Katsuya Dezaki

http://www.w3.org/2001/XMLSchema#string

Masafumi Kakei

http://www.w3.org/2001/XMLSchema#string

Masashi Yoshida

http://www.w3.org/2001/XMLSchema#string

Oleg Dyachok

http://www.w3.org/2001/XMLSchema#string

Tomoyuki Kurashina

http://www.w3.org/2001/XMLSchema#string

Toshihiko Yada

http://www.w3.org/2001/XMLSchema#string

P2860

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

A receptor in pituitary and hypothalamus that functions in growth hormone release

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

Ghrelin octanoylation mediated by an orphan lipid transferase

Triggering and amplifying pathways of regulation of insulin secretion by glucose.

A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo.

Mechanisms of inhibition of insulin release.

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone

Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance

P304

2315-2324

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.2337/DB11-0368

http://www.w3.org/2001/XMLSchema#string

P407

P433

9

http://www.w3.org/2001/XMLSchema#string

P478

60

http://www.w3.org/2001/XMLSchema#string

P50

P577

2011-07-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51520629

http://www.w3.org/2001/XMLSchema#string

P698

21788571

http://www.w3.org/2001/XMLSchema#string

P932

3161328

http://www.w3.org/2001/XMLSchema#string