Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor.
about
Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).The transcriptional regulation of the human CYP2C genesCharacterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis.The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier.Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.Neonatal activation of the nuclear receptor CAR results in epigenetic memory and permanent change of drug metabolism in mouse liverCytochrome P450 regulation by α-tocopherol in Pxr-null and PXR-humanized miceMidazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymesThe Nrf2 activator oltipraz also activates the constitutive androstane receptor.Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations.Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liverA concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures.Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice.Nuclear hormone receptors PXR and CAR and metabolic diseases.Intestinal flora induces the expression of Cyp3a in the mouse liver.Association of a reactive intermediate derived from 1',6-dihydroxy metabolite with benzbromarone-induced hepatotoxicity.
P2860
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P2860
Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Phenytoin induction of the cyp ...... stitutive androstane receptor.
@ast
Phenytoin induction of the cyp ...... stitutive androstane receptor.
@en
type
label
Phenytoin induction of the cyp ...... stitutive androstane receptor.
@ast
Phenytoin induction of the cyp ...... stitutive androstane receptor.
@en
prefLabel
Phenytoin induction of the cyp ...... stitutive androstane receptor.
@ast
Phenytoin induction of the cyp ...... stitutive androstane receptor.
@en
P2093
P2860
P356
P1476
Phenytoin induction of the cyp ...... stitutive androstane receptor.
@en
P2093
Jonathan P Jackson
Joyce A Goldstein
Masahiko Negishi
Stephen S Ferguson
P2860
P304
P356
10.1124/DMD.106.012005
P577
2006-08-25T00:00:00Z