Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth.
about
Rb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cellsFunctional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1Cloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RBMutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteinsPhosphorylation of the PTEN tail regulates protein stability and functionpRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4FCells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycleA novel Rb- and p300-binding protein inhibits transactivation by MyoDEbp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulationLEK1 is a potential inhibitor of pocket protein-mediated cellular processesThe retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expressionA Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells.A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblastsRb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signalsInhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated proteinRegulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathwayActivation of alpha1A-adrenergic receptor promotes differentiation of rat-1 fibroblasts to a smooth muscle-like phenotypeRetinoblastoma tumor suppressor functions shared by stem cell and cancer cell strategiesTargeted drugs in small-cell lung cancerOrigins, genetic landscape, and emerging therapies of small cell lung cancerTwists in views on RB functions in cellular signaling, metabolism and stem cellsUnderstanding pRb: toward the necessary development of targeted treatments for retinoblastomaCritical role of the Rb family in myoblast survival and fusionHuman UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwaySWI/SNF-directed stem cell lineage specification: dynamic composition regulates specific stages of skeletal myogenesisEmerging links between E2F control and mitochondrial functionCyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activityHistone H3K4 demethylases are essential in development and differentiationWnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in miceGenetic interaction between Rb and K-ras in the control of differentiation and tumor suppressionRetinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcriptionThe retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and developmentSubcellular compartmentalization of E2F family members is required for maintenance of the postmitotic state in terminally differentiated muscleFunctional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding proteinRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexesKelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 ComplexThe N Terminus of the Retinoblastoma Protein Inhibits DNA Replication via a Bipartite Mechanism Disrupted in Partially Penetrant Retinoblastomas.Conditional deletion of the retinoblastoma (Rb) gene in ovarian granulosa cells leads to premature ovarian failure.
P2860
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P2860
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Stable binding to E2F is not r ...... nd suppress tumor cell growth.
@ast
Stable binding to E2F is not r ...... nd suppress tumor cell growth.
@en
type
label
Stable binding to E2F is not r ...... nd suppress tumor cell growth.
@ast
Stable binding to E2F is not r ...... nd suppress tumor cell growth.
@en
prefLabel
Stable binding to E2F is not r ...... nd suppress tumor cell growth.
@ast
Stable binding to E2F is not r ...... nd suppress tumor cell growth.
@en
P2093
P2860
P356
P1433
P1476
Stable binding to E2F is not r ...... nd suppress tumor cell growth.
@en
P2093
A B Lassar
B G Novitch
G A Otterson
W R Sellers
P2860
P304
P356
10.1101/GAD.12.1.95
P577
1998-01-01T00:00:00Z