Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice.
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Targeting the endocannabinoid system with cannabinoid receptor agonists: pharmacological strategies and therapeutic possibilitiesCannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritisSelective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.Type 1 cannabinoid receptor ligands display functional selectivity in a cell culture model of striatal medium spiny projection neurons.Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models.Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites.Attenuation of cystitis and pain sensation in mice lacking fatty acid amide hydrolaseCannabinoid receptor 2 as a potential therapeutic target in rheumatoid arthritisAnti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.Repeated low-dose administration of the monoacylglycerol lipase inhibitor JZL184 retains cannabinoid receptor type 1-mediated antinociceptive and gastroprotective effects.The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model.Protective Action of Anandamide and Its COX-2 Metabolite against l-Homocysteine-Induced NLRP3 Inflammasome Activation and Injury in Podocytes.Increased anandamide uptake by sensory neurons contributes to hyperalgesia in a model of cancer painRobust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain.Cannabinoids: novel therapies for arthritis?G protein-coupled receptors in rheumatology.Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands.Mechanisms and Mediators That Drive Arthritis Pain.The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain.Pain in rheumatoid arthritis: models and mechanisms.The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB2, TRPV1, TRPA1 and yet unidentified receptor targets.Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints.The effect of FAAH, MAGL, and Dual FAAH/MAGL inhibition on inflammatory and colorectal distension-induced visceral pain models in Rodents.Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration.Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus.Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to cannabinoid receptors activation in mice.Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid systemThe Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension
P2860
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P2860
Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Fatty acid amide hydrolase blo ...... thermal hyperalgesia in mice.
@ast
Fatty acid amide hydrolase blo ...... thermal hyperalgesia in mice.
@en
type
label
Fatty acid amide hydrolase blo ...... thermal hyperalgesia in mice.
@ast
Fatty acid amide hydrolase blo ...... thermal hyperalgesia in mice.
@en
prefLabel
Fatty acid amide hydrolase blo ...... thermal hyperalgesia in mice.
@ast
Fatty acid amide hydrolase blo ...... thermal hyperalgesia in mice.
@en
P2093
P2860
P1476
Fatty acid amide hydrolase blo ...... thermal hyperalgesia in mice.
@en
P2093
Aron H Lichtman
David T Dudley
Pattipati S Naidu
Steven G Kinsey
P2860
P304
P356
10.1016/J.PBB.2011.06.022
P407
P577
2011-06-29T00:00:00Z