The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
about
Enzymes of the cyclooxygenase pathways of prostanoid biosynthesisIdentification of CD13, CD107a, and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-dependent upregulationUpdate on the status of DP2 receptor antagonists; from proof of concept through clinical failures to promising new drugsPGH1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2Nm23-H2 interacts with a G protein-coupled receptor to regulate its endocytosis through an Rac1-dependent mechanism.Prostanoid receptor antagonists: development strategies and therapeutic applicationsNovel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.CRTH2 expression on T cells in asthma.Expression of DP2 (CRTh2), a prostaglandin D₂ receptor, in human mast cells.Chemoattractant receptor homologous to the T helper 2 cell (CRTH2) is not expressed in human amniocytes and myocytes.Prostaglandins in the eye: Function, expression, and roles in glaucoma.Dexamethasone protects neonatal hypoxic-ischemic brain injury via L-PGDS-dependent PGD2-DP1-pERK signaling pathway.Inverse agonist and pharmacochaperone properties of MK-0524 on the prostanoid DP1 receptorD prostanoid receptor 2 (chemoattractant receptor-homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cellsProstaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2.Activation of the prostaglandin D2 metabolic pathway in Crohn's disease: involvement of the enteric nervous systemChanges in the Th1:Th2 cytokine bias in pregnancy and the effects of the anti-inflammatory cyclopentenone prostaglandin 15-deoxy-Δ(12,14)-prostaglandin J2Differential expression of T cell-related genes in AMI and SA stages of coronary artery disease.Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn.Anti- and proinflammatory effects of 15-deoxy-delta-prostaglandin J2(15d-PGJ2) on human eosinophil functions.Lipocalin-prostaglandin D synthase is a critical beneficial factor in transient and permanent focal cerebral ischemia.CXCR3, CCR5, and CRTH2 Chemokine Receptor Expression in Lymphocytes Infiltrating Thyroid Nodules with Coincident Hashimoto's Thyroiditis Obtained by Fine Needle Aspiration Biopsy.The mechanism and mitigation of niacin-induced flushing.Immune Cell Repertoire and Their Mediators in Patients with Acute Myocardial Infarction or Stable Angina Pectoris.Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells.Prostaglandins in pathogenesis and treatment of multiple sclerosis.Prostaglandin D₂ and T(H)2 inflammation in the pathogenesis of bronchial asthma.Targeting the PGD2/CRTH2/DP1 Signaling Pathway in Asthma and Allergic Disease: Current Status and Future Perspectives.Investigational prostaglandin D2 receptor antagonists for airway inflammation.Prostaglandin D2 receptor antagonists in early development as potential therapeutic options for asthma.Regulation of inflammation by lipid mediators in oral diseases.Current complications and treatment of aspirin-exacerbated respiratory disease.Novel association between vasoactive intestinal peptide and CRTH2 receptor in recruiting eosinophils: a possible biochemical mechanism for allergic eosinophilic inflammation of the airways.Association of CRTH2 gene polymorphisms with the required dose of antihistamines in patients with chronic urticaria.Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease.Prostanoid receptor expression by human airway smooth muscle cells and regulation of the secretion of granulocyte colony-stimulating factor.Prostaglandin D2 mediates neuronal protection via the DP1 receptor.The CRTH2 agonist Pyl A prevents lipopolysaccharide-induced fetal death but induces preterm labour.Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa.
P2860
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P2860
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
@ast
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
@en
type
label
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
@ast
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
@en
prefLabel
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
@ast
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
@en
P1476
The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes.
@en
P2093
Hiroyuki Hirai
Kinya Nagata
P304
P356
10.1016/S0952-3278(03)00078-4
P577
2003-08-01T00:00:00Z