Kappa chain monoallelic demethylation and the establishment of allelic exclusion. - Wikidata - wikimedia - TriplyDB

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

http://www.wikidata.org/entity/Q35202527

about

The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome DNA methylation maintains allele-specific KIR gene expression in human natural killer cells B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5 Immunoglobulin heavy chain exclusion in the shark Dual DNA methylation patterns in the CNS reveal developmentally poised chromatin and monoallelic expression of critical genes.Clonally stable Vκ allelic choice instructs Igκ repertoire.P15INK4b gene methylation and myelodysplastic syndromes.TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon.Receptor selection in B and T lymphocytes.Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes.Genome-wide DNA methylation analysis in cohesin mutant human cell lines.The ataxia telangiectasia mutated and cyclin D3 proteins cooperate to help enforce TCRβ and IgH allelic exclusion Epigenetic control of recombination in the immune system Gene segment selection in V(D)J recombination: accessibility and beyond.Receptor editing in lymphocyte development and central tolerance.Localized DNA demethylation at recombination intermediates during immunoglobulin heavy chain gene assembly.Epigenetic regulation of monoallelic rearrangement (allelic exclusion) of antigen receptor genes.Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism.Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.The Igκ gene enhancers, E3' and Ed, are essential for triggering transcription Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.A multistep mechanism for the activation of rearrangement in the immune system Chromatin dynamics and locus accessibility in the immune system.The establishment and maintenance of lymphocyte identity through gene silencing.Nuclear matrix attachment regions antagonize methylation-dependent repression of long-range enhancer-promoter interactions.Regulating antigen-receptor gene assembly.Chromatin remodeling directly activates V(D)J recombination.Selective gene expression in multigene families from yeast to mammals.Regulation of V(D)J recombination by nucleosome positioning at recombination signal sequences Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4.Epigenetic regulation of lymphoid specific gene sets.Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci.A targeted deletion of a region upstream from the Jkappa cluster impairs kappa chain rearrangement in cis in mice and in the 103/bcl2 cell line.Biallelic germline transcription at the kappa immunoglobulin locus Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells.NF-kappaB and the immunoglobulin kappa gene enhancer.Association between DNA methylation and shortened survival in patients with advanced colorectal cancer treated with 5-fluorouracil based chemotherapy.The Downstream Transcriptional Enhancer, Ed, positively regulates mouse Ig kappa gene expression and somatic hypermutation.Chromatin accessibility and epigenetic modifications differ between frequently and infrequently rearranging VH genes

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P2860

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

http://www.wikidata.org/entity/Q35202527

description

1998 nî lūn-bûn

@nan

1998 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հունիսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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name

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

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Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

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type

label

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

@ast

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

@en

prefLabel

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

@ast

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

@en

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Genes & Development

P1476

Kappa chain monoallelic demethylation and the establishment of allelic exclusion.

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P2093

A Chess

http://www.w3.org/2001/XMLSchema#string

A Kirillov

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H Cedar

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N Singh

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R Mostoslavsky

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R Pelanda

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Y Bergman

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P2860

Detection of specific sequences among DNA fragments separated by gel electrophoresis

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

RAG-1-deficient mice have no mature B and T lymphocytes

Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans

TCR beta and TCR alpha gene enhancers confer tissue- and stage-specificity on V(D)J recombination events.

Allelic inactivation regulates olfactory receptor gene expression.

The V(D)J recombination activating gene, RAG-1.

Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

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1801-1811

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10.1101/GAD.12.12.1801

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12

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12

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1998-06-01T00:00:00Z

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13646326

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9637682

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316908

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