Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugs.
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Pathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine modelA macrophage cell model for selective metalloproteinase inhibitor designIdentification of human cyclooxegenase-2 inhibitors from Cyperus scariosus (R.Br) rhizomes.Potent natural products and herbal medicines for treating liver fibrosisThe effect of Zingiber officinale R. rhizomes (ginger) on plasma pro-inflammatory cytokine levels in well-trained male endurance runners.Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolaseThe Protective Effect of Eupatilin against Hydrogen Peroxide-Induced Injury Involving 5-Lipoxygenase in Feline Esophageal Epithelial Cells.Cysteinyl leukotrienes mediate the enhancing effects of indomethacin and aspirin on eosinophil production in murine bone marrow cultures.Potent multitarget FAAH-COX inhibitors: Design and structure-activity relationship studies.Drug-induced immunomodulation to affect the development and progression of atherosclerosis: a new opportunity?Cyclooxygenase-2 and 5-lipoxygenase in dogs with chronic enteropathies.Perna canaliculus lipid complex PCSO-524™ demonstrated pain relief for osteoarthritis patients benchmarked against fish oil, a randomized trial, without placebo control.3-[5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl]propionic acid and the corresponding methyl ester3-[1-(4-Sulfamoylphenyl)-5-p-tolyl-1H-pyrazol-3-yl]propanoic acid and 3-[5-(4-bromophenyl)-1-(4-sulfamoylphenyl)-1H-pyrazol-3-yl]propanoic acid-dichloromethane-diethyl ether-water (2/0.72/1/1).Cyclooxygenase inhibitors: scope of their use and development in cancer chemotherapy.5-Lipoxygenase metabolic contributions to NSAID-induced organ toxicity.Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships.The anti-inflammatory effects of Yunnan Baiyao are involved in regulation of the phospholipase A2/arachidonic acid metabolites pathways in acute inflammation rat model.Multiple target-centric strategy to tame inflammation.Synthesis, evaluation and modeling of some triazolothienopyrimidinones as anti-inflammatory and antimicrobial agents.The Lipoxygenases: Their Regulation and Implication in Alzheimer's Disease.New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.In vitro immunomodulatory activity and in vivo anti-inflammatory and analgesic potential with gastroprotective effect of the Mediterranean red alga Laurencia obtusa.2-Arylbenzo[b]furan derivatives as potent human lipoxygenase inhibitors.Bioengineered Colorectal Cancer Drugs: Orally Delivered Anti-Inflammatory Agents.Anti-inflammatory Activity of Magnesium Isoglycyrrhizinate Through Inhibition of Phospholipase A2/Arachidonic Acid Pathway.Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Progress in Small Molecule Drug Development.Modulation of Cox-1, 5-, 12- and 15-Lox by popular herbal remedies used in southern Italy against psoriasis and other skin diseases.Synthesis, analgesic and anti-inflammatory activities of new methyl-imidazolyl-1,3,4-oxadiazoles and 1,2,4-triazoles.Investigation of the effect of phlomisoside F on complete Freund's adjuvant-induced arthritis.Synthesis and hepatoprotective properties of Acanthus ilicifolius alkaloid A and its derivatives.Anti-inflammatory effects of zingiber officinale in type 2 diabetic patientsImproved Antitumor Activity of a Therapeutic Melanoma Vaccine through the Use of the Dual COX-2/5-LO Inhibitor LicofeloneChronic Brain Inflammation: The Neurochemical Basis for Drugs to Reduce Inflammation.New Insight into the SAR of Pyrimido [4,5-b][1,4] Benzothiazines as 15-lipoxygenase Inhibitors.Synthesis and evaluation of 5-lipoxygenase translocation inhibitors from acylnitroso hetero-Diels-Alder cycloadducts.Protective effects of ginger-turmeric rhizomes mixture on joint inflammation, atherogenesis, kidney dysfunction and other complications in a rat model of human rheumatoid arthritis.Discovery of potential anti-inflammatory drugs: diaryl-1,2,4-triazoles bearing N-hydroxyurea moiety as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.Synthesis and SAR comparative studies of 2-allyl-4-methoxy-1-alkoxybenzenes as 15-lipoxygenase inhibitors.
P2860
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P2860
Dual inhibition of cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) as a new strategy to provide safer non-steroidal anti-inflammatory drugs.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Dual inhibition of cyclooxygen ...... oidal anti-inflammatory drugs.
@ast
Dual inhibition of cyclooxygen ...... oidal anti-inflammatory drugs.
@en
type
label
Dual inhibition of cyclooxygen ...... oidal anti-inflammatory drugs.
@ast
Dual inhibition of cyclooxygen ...... oidal anti-inflammatory drugs.
@en
prefLabel
Dual inhibition of cyclooxygen ...... oidal anti-inflammatory drugs.
@ast
Dual inhibition of cyclooxygen ...... oidal anti-inflammatory drugs.
@en
P1476
Dual inhibition of cyclooxygen ...... oidal anti-inflammatory drugs.
@en
P2093
Caroline Charlier
Catherine Michaux
P304
P356
10.1016/S0223-5234(03)00115-6
P577
2003-07-01T00:00:00Z