Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease - Wikidata - wikimedia - TriplyDB

Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease

Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease

http://www.wikidata.org/entity/Q35205918

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Niemann-Pick disease type C Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome Diagnostic workup and management of patients with suspected Niemann-Pick type C disease Current trends in oxysterol research Niemann-Pick disease type C symptomatology: an expert-based clinical description Genetic and laboratory diagnostic approach in Niemann Pick disease type C Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease Genetic dissection of a cell-autonomous neurodegenerative disorder: lessons learned from mouse models of Niemann-Pick disease type C Genomic expression analyses reveal lysosomal, innate immunity proteins, as disease correlates in murine models of a lysosomal storage disorder Recent advances in the diagnosis and treatment of niemann-pick disease type C in children: a guide to early diagnosis for the general pediatrician Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain Alteration of gene expression profile in Niemann-Pick type C mice correlates with tissue damage and oxidative stress Niemann-Pick C disease gene mutations and age-related neurodegenerative disorders Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease Fostering collaborative research for rare genetic disease: the example of niemann-pick type C disease The hidden Niemann-Pick type C patient: clinical niches for a rare inherited metabolic disease.Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease.Adult-Onset Niemann-Pick Disease Type C: Rapid Treatment Initiation Advised but Early Diagnosis Remains Difficult Understanding the Apothecaries Within: The Necessity of a Systematic Approach for Defining the Chemical Output of the Human Microbiome Miglustat: a review of its use in Niemann-Pick disease type C.Diagnostic and treatment implications of psychosis secondary to treatable metabolic disorders in adults: a systematic review.Diagnosis of Niemann-Pick disease type C with 7-ketocholesterol screening followed by NPC1/NPC2 gene mutation confirmation in Chinese patients Different oxysterols have opposing actions at N-methyl-D-aspartate receptors.Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin Genetic connections between neurological disorders and cholesterol metabolism Psychiatric signs and symptoms in treatable inborn errors of metabolism.Early steps in steroidogenesis: intracellular cholesterol trafficking.Altered transition metal homeostasis in Niemann-Pick disease, type C1.Cholesterol homeostatic responses provide biomarkers for monitoring treatment for the neurodegenerative disease Niemann-Pick C1 (NPC1)Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents.Saccadic eye movement characteristics in adult Niemann-Pick Type C disease: relationships with disease severity and brain structural measures.Cholesterol in brain disease: sometimes determinant and frequently implicated.Aging in the canine and feline brain Plasma lysosphingomyelin demonstrates great potential as a diagnostic biomarker for Niemann-Pick disease type C in a retrospective study A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma.Altered vitamin E status in Niemann-Pick type C disease.Lipidomics at the interface of structure and function in systems biology Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress.β-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease.

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Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease

http://www.wikidata.org/entity/Q35205918

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Cholesterol oxidation products ...... rs for Niemann-Pick C1 disease

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Cholesterol oxidation products ...... rs for Niemann-Pick C1 disease

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Cholesterol oxidation products ...... rs for Niemann-Pick C1 disease

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Cholesterol oxidation products ...... rs for Niemann-Pick C1 disease

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Cholesterol oxidation products ...... rs for Niemann-Pick C1 disease

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Cholesterol oxidation products ...... rs for Niemann-Pick C1 disease

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SCITRANSLMED.3001417

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Science Translational Medicine

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Cholesterol oxidation products ...... rs for Niemann-Pick C1 disease

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Charles Vite

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Dana Olzeski

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Daniel S Ory

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David E Scherrer

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Dennis J Dietzen

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Forbes D Porter

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John House

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Michael H Lanier

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Nicole M Yanjanin

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P2860

Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression

Identification of HE1 as the second gene of Niemann-Pick C disease

NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

2-hydroxypropyl-beta-cyclodextrin raises hearing threshold in normal cats and in cats with Niemann-Pick type C disease

Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking

Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease

Lathosterolosis: an inborn error of human and murine cholesterol synthesis due to lathosterol 5-desaturase deficiency

Epoxide hydrolases: their roles and interactions with lipid metabolism

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

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56

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Christopher A Wassif

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2010-11-01T00:00:00Z

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