Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
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Inflammasome/IL-1β Responses to Streptococcal PathogensRegulation of Nlrp3 inflammasome by dietary metabolitesThe intersection of cell death and inflammasome activationCritical role of P2X7 receptors in the neuroinflammation and cognitive dysfunction after surgery.Free immunoglobulin light chain (FLC) promotes murine colitis and colitis-associated colon carcinogenesis by activating the inflammasome.Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular.Peptidoglycan Branched Stem Peptides Contribute to Streptococcus pneumoniae Virulence by Inhibiting Pneumolysin Release.Sensing of interleukin-1 cytokines during Streptococcus pneumoniae colonization contributes to macrophage recruitment and bacterial clearance.Immune Interactions with Pathogenic and Commensal Fungi: A Two-Way StreetNeutrophils Directly Recognize Group B Streptococci and Contribute to Interleukin-1β Production during Infection.β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice.Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.Interferon Regulatory Factor-1 Mediates Alveolar Macrophage Pyroptosis During LPS-Induced Acute Lung Injury in Mice.Post-translational regulation of inflammasomes.A safety evaluation of canakinumab for the treatment of systemic onset juvenile idiopathic arthritis.Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia.Inflammasomes in Pneumococcal Infection: Innate Immune Sensing and Bacterial Evasion Strategies.Inflammasomes link vascular disease with neuroinflammation and brain disorders.Proteomics in the Study of Bacterial Keratitis.α-Linoleic acid enhances the capacity of α-1 antitrypsin to inhibit lipopolysaccharide-induced IL-1β in human blood neutrophilsCorneal Fibroblasts as Sentinel Cells and Local Immune Modulators in Infectious Keratitis.Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae.Reactive Oxygen Species Localization Programs Inflammation to Clear Microbes of Different Size.Exposure to a Social Stressor Induces Translocation of Commensal Lactobacilli to the Spleen and Priming of the Innate Immune System.Oral recombinant human or mouse lactoferrin reduces Mycobacterium tuberculosis TDM induced granulomatous lung pathology.NLRP3 inflammasome mediates interleukin-1β production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in mice.The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists.Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretionNAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease.Casticin inhibits interleukin-1β-induced ICAM-1 and MUC5AC expression by blocking NF-κB, PI3K-Akt, and MAPK signaling in human lung epithelial cells.MCC950, the selective NLRP3 inflammasome inhibitor protects mice against traumatic brain injury.Chlamydia abortus Pmp18.1 Induces IL-1β Secretion by TLR4 Activation through the MyD88, NF-κB, and Caspase-1 Signaling Pathways.Simultaneous Detection of Cellular Viability and Interleukin-1β Secretion from Single Cells by ELISpot.NLRP3 Inflammasome Activation in Aged Macrophages is diminished during Streptococcus pneumoniae Infection.Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection.Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.
P2860
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P2860
Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
name
Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.
@ast
Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.
@en
type
label
Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.
@ast
Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.
@en
prefLabel
Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.
@ast
Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.
@en
P2093
P2860
P50
P356
P1476
Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.
@en
P2093
Amy G Hise
Andrew Camilli
Eric Pearlman
Hesham A Malak
Michael Katsnelson
Neil G Greene
Scott J Howell
P2860
P304
P356
10.4049/JIMMUNOL.1401624
P407
P577
2015-01-21T00:00:00Z