Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux. - Wikidata - wikimedia - TriplyDB

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

http://www.wikidata.org/entity/Q35206149

about

Inflammasome/IL-1β Responses to Streptococcal Pathogens Regulation of Nlrp3 inflammasome by dietary metabolites The intersection of cell death and inflammasome activation Critical role of P2X7 receptors in the neuroinflammation and cognitive dysfunction after surgery.Free immunoglobulin light chain (FLC) promotes murine colitis and colitis-associated colon carcinogenesis by activating the inflammasome.Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular.Peptidoglycan Branched Stem Peptides Contribute to Streptococcus pneumoniae Virulence by Inhibiting Pneumolysin Release.Sensing of interleukin-1 cytokines during Streptococcus pneumoniae colonization contributes to macrophage recruitment and bacterial clearance.Immune Interactions with Pathogenic and Commensal Fungi: A Two-Way Street Neutrophils Directly Recognize Group B Streptococci and Contribute to Interleukin-1β Production during Infection.β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.Inhibition of Alveolar Macrophage Pyroptosis Reduces Lipopolysaccharide-induced Acute Lung Injury in Mice.Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP.Interferon Regulatory Factor-1 Mediates Alveolar Macrophage Pyroptosis During LPS-Induced Acute Lung Injury in Mice.Post-translational regulation of inflammasomes.A safety evaluation of canakinumab for the treatment of systemic onset juvenile idiopathic arthritis.Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia.Inflammasomes in Pneumococcal Infection: Innate Immune Sensing and Bacterial Evasion Strategies.Inflammasomes link vascular disease with neuroinflammation and brain disorders.Proteomics in the Study of Bacterial Keratitis.α-Linoleic acid enhances the capacity of α-1 antitrypsin to inhibit lipopolysaccharide-induced IL-1β in human blood neutrophils Corneal Fibroblasts as Sentinel Cells and Local Immune Modulators in Infectious Keratitis.Pneumolysin-Dependent Calpain Activation and Interleukin-1α Secretion in Macrophages Infected with Streptococcus pneumoniae.Reactive Oxygen Species Localization Programs Inflammation to Clear Microbes of Different Size.Exposure to a Social Stressor Induces Translocation of Commensal Lactobacilli to the Spleen and Priming of the Innate Immune System.Oral recombinant human or mouse lactoferrin reduces Mycobacterium tuberculosis TDM induced granulomatous lung pathology.NLRP3 inflammasome mediates interleukin-1β production in immune cells in response to Acinetobacter baumannii and contributes to pulmonary inflammation in mice.The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists.Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease.Casticin inhibits interleukin-1β-induced ICAM-1 and MUC5AC expression by blocking NF-κB, PI3K-Akt, and MAPK signaling in human lung epithelial cells.MCC950, the selective NLRP3 inflammasome inhibitor protects mice against traumatic brain injury.Chlamydia abortus Pmp18.1 Induces IL-1β Secretion by TLR4 Activation through the MyD88, NF-κB, and Caspase-1 Signaling Pathways.Simultaneous Detection of Cellular Viability and Interleukin-1β Secretion from Single Cells by ELISpot.NLRP3 Inflammasome Activation in Aged Macrophages is diminished during Streptococcus pneumoniae Infection.Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection.Neutrophils drive alveolar macrophage IL-1β release during respiratory viral infection.Pneumolysin induced mitochondrial dysfunction leads to release of mitochondrial DNA.

P2860

Q26779173-DA773736-4D0A-476B-BCCF-E0E5B0F6808D Q28078340-D7262449-03CD-4346-B538-1C6BB6B851C2 Q28274739-E9985C5A-362E-4F4D-96D3-BD53C8C63494 Q30274994-EFAC650B-BEE2-49B6-A1C5-A6A30594A830 Q33899492-F3D6B0D7-67B2-49EB-9C3D-7AC9C81529B3 Q35662239-EE25465F-AE55-4BDF-9C0D-B8E997AE568A Q35675396-25D58988-4CBB-47AA-BC54-F8606E826CF0 Q35833831-CBF6BE4F-99AB-4F12-A738-727DC788BB64 Q35847333-4A02B5B2-4BB4-4D53-947D-CE30F26D379C Q36100363-454665E1-04D3-4DC4-9E5E-2F6407ED1690 Q36294205-1F1429B1-4C2C-4705-B995-E1FDF47EEBB0 Q36531774-185755EB-C427-47F7-9E23-3CD33CA77B63 Q36587518-3F3D8DDA-882F-476C-B61E-0BCD991DB0C6 Q37162331-095D4B4D-0B33-449E-A14A-5632900FEB8A Q37559665-09E7AE7F-0076-4D47-AC22-9CBF8DDD36E7 Q38633441-F0CFAC87-918A-46F8-A84E-3E1001B0322B Q38795315-E281B232-03CB-48F4-ABCA-5892596B3A1E Q38810592-03B512AD-C866-4F49-B875-0C8438CCEC1E Q38909299-D2919D88-C122-4325-ABE3-53617A211DE0 Q38916890-F4D5BED6-E878-44DE-9284-A037597377BF Q39156160-B3F719CD-984A-4A75-8E74-D8112A4AFAA8 Q39565971-9A3F0C59-808F-4F6F-AF43-48EB1156FFE2 Q40083114-137FD9F7-D3A1-4414-B75C-34C6476F7F68 Q40166389-DC1AF339-398D-4AE1-9064-E47F43DADD64 Q40289845-7E28C7FA-C59F-40C5-85DB-14EE9A94BDC8 Q40342621-2D58082B-EDD6-47B7-BE36-9AE542286514 Q40343798-64FE16A4-96B7-4923-BDB0-5AAAECF55195 Q40391889-4238986F-9175-41B8-8F16-7A5140EB63F4 Q40721540-4A5294DC-2CC1-457E-95BB-07C576B89AED Q41851303-53D26979-09B5-4830-BFC6-F6E71A89B4A8 Q42709957-5983BDDC-B5C9-4DDA-90B5-3D79262F805B Q47137440-CAD9D917-37B6-42CF-9E27-4E6CF55EB1DF Q47155326-418B3004-3ABB-4715-885E-F64BBA3B92C5 Q47237235-E2F2ED0B-A824-43B1-8C05-0F74E7544F2A Q47352451-633E18F2-5325-426B-905E-81C7991EF79B Q47361966-6C812E52-7F81-49B8-A9CC-841BD4E74845 Q47447801-AA7DBC00-EBBC-46EA-ACFD-AB7AF44BA881 Q47569725-08EA54D5-5964-4F73-9519-14DDE0656586 Q47592796-4E92D406-EE1B-4E62-8582-C445328F32DF Q47661761-7878B95A-8147-4E0B-9FFA-6A4B329ED12C

P2860

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

http://www.wikidata.org/entity/Q35206149

description

2015 nî lūn-bûn

@nan

2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年学术文章

@wuu

2015年学术文章

@zh-cn

2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

name

Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.

@ast

Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.

@en

type

label

Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.

@ast

Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.

@en

prefLabel

Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.

@ast

Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.

@en

P1433

Q35206149-BE67A4CC-2717-4398-B0C0-F5A38EDDC65D

P1476

Q35206149-C66DCB86-C231-4075-86B0-7A61B54250D5

P2093

Q35206149-1593BE43-F719-46AD-9631-B4A241397012

Q35206149-1CC6C3B3-DF87-4F52-982A-EFC2E94F91F0

Q35206149-3ABA058B-1448-43DA-9695-CAF9F2B9F0A9

Q35206149-42CAF113-5DD0-4BD9-ADEB-D9A978E9F7D6

Q35206149-96DCB04D-6FFA-465B-9A6F-BD2300AA22B6

Q35206149-E9755C80-E032-43EE-8806-7D794EF24CEB

Q35206149-FA20F980-8917-4EE2-BEA1-5BF1A9430A1C

P2860

Q35206149-04DDC776-73F9-4B1C-8514-17D142EDAFC3

Q35206149-0BDC9D62-892E-4C26-BC7F-0996C68E4CB9

Q35206149-1206CF1B-7248-4C91-AEED-3B51F725CCDE

Q35206149-12FA1F2B-573C-452D-8829-ED87C2999EDE

Q35206149-15A05A0E-0B6B-4D39-BEEB-5C1D7FAD3A03

Q35206149-2122D8DD-0027-43ED-B8F3-F890ACAFA410

Q35206149-221A5552-C742-47F2-B48A-23C4642C6984

Q35206149-241DC871-4670-419B-8658-4B7E20A68716

Q35206149-26599741-4F96-416A-953E-FBED36DD74D2

Q35206149-30701BE5-247D-4000-B8EB-C8EBAD6086D9

P304

Q35206149-03FBADDC-1356-406B-872C-7C2FA373B42A

P31

Q35206149-75CB6E92-782F-4901-9764-3940D28019FE

P356

Q35206149-B052A068-8E1C-48A8-9893-463F4D37DE4C

P407

Q35206149-161396FC-C3DF-4A3A-AEF7-5150A68B8A27

P433

Q35206149-4FB4D76D-E59F-425C-B268-459671982484

P478

Q35206149-9AC37B12-185C-4E7F-98D2-DB7419911659

P50

Q35206149-666FD76A-D573-407A-A3BB-AAB6DD955940

Q35206149-918BAAD3-C012-4831-8EC7-FC62739173F8

Q35206149-F7D5A08B-38D0-4146-8C08-0D5FD4C0D4FB

P577

Q35206149-D02A7D09-896D-428F-84CA-EB6DF3A9AE31

P5875

Q35206149-F7F63203-D22F-4AD0-964F-DDC4B72CE034

P698

Q35206149-672B3747-672A-41C1-91C0-2EBF70EA92C8

P932

Q35206149-CA66FE10-6A71-428B-9496-8B4EEC6F0F38

P356

JIMMUNOL.1401624

P1433

Journal of Immunology

P1476

Neutrophil IL-1β processing in ...... and is dependent on K+ efflux.

@en

P2093

Amy G Hise

http://www.w3.org/2001/XMLSchema#string

Andrew Camilli

http://www.w3.org/2001/XMLSchema#string

Eric Pearlman

http://www.w3.org/2001/XMLSchema#string

Hesham A Malak

http://www.w3.org/2001/XMLSchema#string

Michael Katsnelson

http://www.w3.org/2001/XMLSchema#string

Neil G Greene

http://www.w3.org/2001/XMLSchema#string

Scott J Howell

http://www.w3.org/2001/XMLSchema#string

P2860

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Neutrophil extracellular traps kill bacteria

Structural basis of pore formation by the bacterial toxin pneumolysin

The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Activation and regulation of the inflammasomes

Neutrophil recruitment and function in health and inflammation

P304

1763-1775

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4049/JIMMUNOL.1401624

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

194

http://www.w3.org/2001/XMLSchema#string

P50

George R. Dubyak

Mausita Karmakar

P577

2015-01-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

271221888

http://www.w3.org/2001/XMLSchema#string

P698

25609842

http://www.w3.org/2001/XMLSchema#string

P932

4369676

http://www.w3.org/2001/XMLSchema#string