Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination
about
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosisAAV-dominant negative tumor necrosis factor (DN-TNF) gene transfer to the striatum does not rescue medium spiny neurons in the YAC128 mouse model of Huntington's diseaseGrowth factors in synaptic function.Systemically administered anti-TNF therapy ameliorates functional outcomes after focal cerebral ischemia.Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice.Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microgliaResilience and Vulnerability to Pain and Inflammation in the Hippocampus.Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy.IL7Rα contributes to experimental autoimmune encephalomyelitis through altered T cell responses and nonhematopoietic cell lineagesNeuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signalingCentral but not systemic administration of XPro1595 is therapeutic following moderate spinal cord injury in miceTargeting anti-inflammatory treatment can ameliorate injury-induced neuropathic pain.Proteasome inhibitor bortezomib suppresses nuclear factor-kappa B activation and ameliorates eye inflammation in experimental autoimmune uveitisAntibody-mediated inhibition of TNFR1 attenuates disease in a mouse model of multiple sclerosis.Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis.Sustained TNF production by central nervous system infiltrating macrophages promotes progressive autoimmune encephalomyelitis.Oligodendroglial TNFR2 Mediates Membrane TNF-Dependent Repair in Experimental Autoimmune Encephalomyelitis by Promoting Oligodendrocyte Differentiation and Remyelination.The TNFα-Transgenic Rat: Hippocampal Synaptic Integrity, Cognition, Function, and Post-Ischemic Cell Loss.Peripheral elevation of TNF-α leads to early synaptic abnormalities in the mouse somatosensory cortex in experimental autoimmune encephalomyelitisConditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling.Inhibition of astroglial NF-κB enhances oligodendrogenesis following spinal cord injury.Essential protective role of tumor necrosis factor receptor 2 in neurodegenerationADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice.Emerging immunopharmacological targets in multiple sclerosis.Opposing Functions of Microglial and Macrophagic TNFR2 in the Pathogenesis of Experimental Autoimmune Encephalomyelitis.Selective effects of a therapeutic protein targeting tumor necrosis factor-alpha on cytochrome P450 regulation during infectious colitis: Implications for disease-dependent drug-drug interactions.Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis.CNS Demyelination with TNF-α BlockersInterrelation of oxidative stress and inflammation in neurodegenerative disease: role of TNF.Disruption of the astrocytic TNFR1-GDNF axis accelerates motor neuron degeneration and disease progression in amyotrophic lateral sclerosis.Further understanding of the immunopathology of multiple sclerosis: impact on future treatments.A clinical conundrum: the detrimental effect of TNF antagonists in multiple sclerosis.Correlation of inducible nitric oxide synthase (iNOS) inhibition with TNF-α, caspase-1, FasL and TLR-3 in pathogenesis of rabies in mouse model.Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia.Fingolimod induces neuroprotective factors in human astrocytes.Peripheral administration of the selective inhibitor of soluble tumor necrosis factor (TNF) XPro®1595 attenuates nigral cell loss and glial activation in 6-OHDA hemiparkinsonian rats.Human interferon regulatory factor 5 homologous epitopes of Epstein-Barr virus and Mycobacterium avium subsp. paratuberculosis induce a specific humoral and cellular immune response in multiple sclerosis patients.TNFR1 inhibition with a Nanobody protects against EAE development in mice.iRHOM2 takes control of rheumatoid arthritis.Circadian rhythmicity of inflammatory serum parameters: a neglected issue in the search of biomarkers in multiple sclerosis.
P2860
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P2860
Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Inhibition of soluble tumour n ...... preservation and remyelination
@ast
Inhibition of soluble tumour n ...... preservation and remyelination
@en
type
label
Inhibition of soluble tumour n ...... preservation and remyelination
@ast
Inhibition of soluble tumour n ...... preservation and remyelination
@en
prefLabel
Inhibition of soluble tumour n ...... preservation and remyelination
@ast
Inhibition of soluble tumour n ...... preservation and remyelination
@en
P2093
P2860
P356
P1433
P1476
Inhibition of soluble tumour n ...... preservation and remyelination
@en
P2093
Anna Dellarole
David E Szymkowski
Jessica Jopek Ashbaugh
John R Bethea
Roberta Brambilla
Roberta Magliozzi
Shaffiat Karmally
P2860
P304
P356
10.1093/BRAIN/AWR199
P407
P577
2011-09-01T00:00:00Z