about
NF023 binding to XIAP-BIR1: searching drugs for regulation of the NF-κB pathwayAbsence of a conserved proline and presence of a conserved tyrosine in the CB2 cannabinoid receptor are crucial for its functionExploration of the ligand binding site of the human 5-HT(4) receptor by site-directed mutagenesis and molecular modelingRibose modified nucleosides and nucleotides as ligands for purine receptorsNeoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosidesConstitutive activation of A(3) adenosine receptors by site-directed mutagenesisAlternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptorC5a receptor activation. Genetic identification of critical residues in four transmembrane helices.Genetic mapping of the human C5a receptor. Identification of transmembrane amino acids critical for receptor function.Olfactory receptor database: a sensory chemoreceptor resourceThe C9 methyl group of retinal interacts with glycine-121 in rhodopsin.Molecular recognition in P2 receptors: ligand development aided by molecular modeling and mutagenesis.Stimulation of adenosine A3 receptors in cerebral ischemia. Neuronal death, recovery, or both?Constitutive activation of the delta opioid receptor by mutations in transmembrane domains III and VII.Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor.Identification of essential residues involved in the allosteric modulation of the human A(3) adenosine receptorQuantitative Analysis of Guanine Nucleotide Exchange Factors (GEFs) as Enzymes.Drug analysis based on signaling responses to G-protein-coupled receptors.Crystal structures of the M1 and M4 muscarinic acetylcholine receptorsPyrimidine nucleotides with 4-alkyloxyimino and terminal tetraphosphate δ-ester modifications as selective agonists of the P2Y(4) receptor.In silico analysis of the binding of agonists and blockers to the β2-adrenergic receptor.Shift in purine/pyrimidine base recognition upon exchanging extracellular domains in P2Y 1/6 chimeric receptors.In silico screening for agonists and blockers of the β(2) adrenergic receptor: implications of inactive and activated state structuresHomology modeling of class a G protein-coupled receptorsA mutational analysis of residues essential for ligand recognition at the human P2Y1 receptor.Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling.Mutagenesis reveals structure-activity parallels between human A2A adenosine receptors and biogenic amine G protein-coupled receptors.The role of amino acids in extracellular loops of the human P2Y1 receptor in surface expression and activation processes.Evidence for the Recognition of Non-Nucleotide Antagonists Within the Transmembrane Domains of the Human P2Y(1) ReceptorNucleotide exchange factors: Kinetic analyses and the rationale for studying kinetics of GEFs.On the applicability of GPCR homology models to computer-aided drug discovery: a comparison between in silico and crystal structures of the beta2-adrenergic receptor.Expression, stability, and membrane integration of truncation mutants of bovine rhodopsinMolecular pharmacology and ligand docking studies reveal a single amino acid difference between mouse and human serotonin 5-HT2A receptors that impacts behavioral translation of novel 4-phenyl-2-dimethylaminotetralin ligandsFluorescent muscarinic EGFP-hM1 chimeric receptors: design, ligand binding and functional properties.DIRECT-ID: An automated method to identify and quantify conformational variations--application to β2 -adrenergic GPCR.Chemokines and their receptors: insights from molecular modeling and crystallography.Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate.Mutational analysis of the antagonist-binding site of the histamine H(1) receptor.A genome-based receptor nomenclature.Modulation of apoptosis by adenosine in the central nervous system: a possible role for the A3 receptor. Pathophysiological significance and therapeutic implications for neurodegenerative disorders.
P2860
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P2860
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Molecular Architecture of G Protein-Coupled Receptors.
@ast
Molecular Architecture of G Protein-Coupled Receptors.
@en
type
label
Molecular Architecture of G Protein-Coupled Receptors.
@ast
Molecular Architecture of G Protein-Coupled Receptors.
@en
prefLabel
Molecular Architecture of G Protein-Coupled Receptors.
@ast
Molecular Architecture of G Protein-Coupled Receptors.
@en
P2860
P1476
Molecular Architecture of G Protein-Coupled Receptors
@en
P2093
A Michiel van Rhee
P2860
P356
10.1002/(SICI)1098-2299(199601)37:1<1::AID-DDR1>3.0.CO;2-S
P577
1996-01-01T00:00:00Z